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Unconventional Peptide Presentation by Classical MHC Class I and Implications for T and NK Cell Activation

T cell-mediated immune recognition of peptides is initiated upon binding of the antigen receptor on T cells (TCR) to the peptide-MHC complex. TCRs are typically restricted by a particular MHC allele, while polymorphism within the MHC molecule can affect the spectrum of peptides that are bound and pr...

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Detalles Bibliográficos
Autor principal: Zajonc, Dirk M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590165/
https://www.ncbi.nlm.nih.gov/pubmed/33066279
http://dx.doi.org/10.3390/ijms21207561

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