Folding Assessment of Incorporation of Noncanonical Amino Acids Facilitates Expansion of Functional‐Group Diversity for Enzyme Engineering

Protein design is limited by the diversity of functional groups provided by the canonical protein „building blocks“. Incorporating noncanonical amino acids (ncAAs) into enzymes enables a dramatic expansion of their catalytic features. For this, quick identification of fully translated and correctly...

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Detalles Bibliográficos
Autores principales: Drienovská, Ivana, Gajdoš, Matúš, Kindler, Alexia, Takhtehchian, Mahsa, Darnhofer, Barbara, Birner‐Gruenberger, Ruth, Dörr, Mark, Bornscheuer, Uwe T., Kourist, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590180/
https://www.ncbi.nlm.nih.gov/pubmed/32347609
http://dx.doi.org/10.1002/chem.202002077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590180/
https://www.ncbi.nlm.nih.gov/pubmed/32347609
http://dx.doi.org/10.1002/chem.202002077

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