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A Wireless Magnetic Resonance Device for Optogenetic Applications in an Animal Model

The currents of optical stimulation devices with tethered or untethered systems have various disadvantages, including optical fiber breakage, disrupted animal movements, heavy batteries carried on heads, and high-frequency electromagnetic impacts. Our novel wireless remote control was developed to a...

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Autores principales: Tsai, Arthur C., Huang, Andrew Chih Wei, Yu, Ying Hao, Kuo, Chii-Shyang, Hsu, Chih-Chan, Lim, Yeou San, Shyu, Bai Chuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590226/
https://www.ncbi.nlm.nih.gov/pubmed/33081369
http://dx.doi.org/10.3390/s20205869
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author Tsai, Arthur C.
Huang, Andrew Chih Wei
Yu, Ying Hao
Kuo, Chii-Shyang
Hsu, Chih-Chan
Lim, Yeou San
Shyu, Bai Chuang
author_facet Tsai, Arthur C.
Huang, Andrew Chih Wei
Yu, Ying Hao
Kuo, Chii-Shyang
Hsu, Chih-Chan
Lim, Yeou San
Shyu, Bai Chuang
author_sort Tsai, Arthur C.
collection PubMed
description The currents of optical stimulation devices with tethered or untethered systems have various disadvantages, including optical fiber breakage, disrupted animal movements, heavy batteries carried on heads, and high-frequency electromagnetic impacts. Our novel wireless remote control was developed to address these issues. The novel wireless device uses a magnetic resonance technique to modify the deficits of the conventional magnetic induction or radio-frequency power sources. The present device emits a strong and steady electromagnetic power. It is cheaper than previous versions, and the receiver coil on its head is very light (≦ 1 g). For the present wireless remote-controlled device, the electromagnetic field’s range (i.e., +5 cm and −5 cm of the outside coil) is larger than the range for the magnetic induction and radio-frequency power sources. The present device controls animals’ behavior by the electromagnetic field’s effective range via photostimulation. The novel wireless remote-controlled device with a magnetic resonance technique can be applied in many behavioral tasks in mice and rats. To avoid the adverse effects of high radio frequency and to extend the electromagnetic field’s range, this novel technique serves as a helpful tool to modulate the neuronal activity of target neurons in specific brain areas for optogenetic experiments.
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spelling pubmed-75902262020-10-29 A Wireless Magnetic Resonance Device for Optogenetic Applications in an Animal Model Tsai, Arthur C. Huang, Andrew Chih Wei Yu, Ying Hao Kuo, Chii-Shyang Hsu, Chih-Chan Lim, Yeou San Shyu, Bai Chuang Sensors (Basel) Article The currents of optical stimulation devices with tethered or untethered systems have various disadvantages, including optical fiber breakage, disrupted animal movements, heavy batteries carried on heads, and high-frequency electromagnetic impacts. Our novel wireless remote control was developed to address these issues. The novel wireless device uses a magnetic resonance technique to modify the deficits of the conventional magnetic induction or radio-frequency power sources. The present device emits a strong and steady electromagnetic power. It is cheaper than previous versions, and the receiver coil on its head is very light (≦ 1 g). For the present wireless remote-controlled device, the electromagnetic field’s range (i.e., +5 cm and −5 cm of the outside coil) is larger than the range for the magnetic induction and radio-frequency power sources. The present device controls animals’ behavior by the electromagnetic field’s effective range via photostimulation. The novel wireless remote-controlled device with a magnetic resonance technique can be applied in many behavioral tasks in mice and rats. To avoid the adverse effects of high radio frequency and to extend the electromagnetic field’s range, this novel technique serves as a helpful tool to modulate the neuronal activity of target neurons in specific brain areas for optogenetic experiments. MDPI 2020-10-16 /pmc/articles/PMC7590226/ /pubmed/33081369 http://dx.doi.org/10.3390/s20205869 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Tsai, Arthur C.
Huang, Andrew Chih Wei
Yu, Ying Hao
Kuo, Chii-Shyang
Hsu, Chih-Chan
Lim, Yeou San
Shyu, Bai Chuang
A Wireless Magnetic Resonance Device for Optogenetic Applications in an Animal Model
title A Wireless Magnetic Resonance Device for Optogenetic Applications in an Animal Model
title_full A Wireless Magnetic Resonance Device for Optogenetic Applications in an Animal Model
title_fullStr A Wireless Magnetic Resonance Device for Optogenetic Applications in an Animal Model
title_full_unstemmed A Wireless Magnetic Resonance Device for Optogenetic Applications in an Animal Model
title_short A Wireless Magnetic Resonance Device for Optogenetic Applications in an Animal Model
title_sort wireless magnetic resonance device for optogenetic applications in an animal model
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590226/
https://www.ncbi.nlm.nih.gov/pubmed/33081369
http://dx.doi.org/10.3390/s20205869
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