Cargando…
A Wireless Magnetic Resonance Device for Optogenetic Applications in an Animal Model
The currents of optical stimulation devices with tethered or untethered systems have various disadvantages, including optical fiber breakage, disrupted animal movements, heavy batteries carried on heads, and high-frequency electromagnetic impacts. Our novel wireless remote control was developed to a...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590226/ https://www.ncbi.nlm.nih.gov/pubmed/33081369 http://dx.doi.org/10.3390/s20205869 |
_version_ | 1783600758922412032 |
---|---|
author | Tsai, Arthur C. Huang, Andrew Chih Wei Yu, Ying Hao Kuo, Chii-Shyang Hsu, Chih-Chan Lim, Yeou San Shyu, Bai Chuang |
author_facet | Tsai, Arthur C. Huang, Andrew Chih Wei Yu, Ying Hao Kuo, Chii-Shyang Hsu, Chih-Chan Lim, Yeou San Shyu, Bai Chuang |
author_sort | Tsai, Arthur C. |
collection | PubMed |
description | The currents of optical stimulation devices with tethered or untethered systems have various disadvantages, including optical fiber breakage, disrupted animal movements, heavy batteries carried on heads, and high-frequency electromagnetic impacts. Our novel wireless remote control was developed to address these issues. The novel wireless device uses a magnetic resonance technique to modify the deficits of the conventional magnetic induction or radio-frequency power sources. The present device emits a strong and steady electromagnetic power. It is cheaper than previous versions, and the receiver coil on its head is very light (≦ 1 g). For the present wireless remote-controlled device, the electromagnetic field’s range (i.e., +5 cm and −5 cm of the outside coil) is larger than the range for the magnetic induction and radio-frequency power sources. The present device controls animals’ behavior by the electromagnetic field’s effective range via photostimulation. The novel wireless remote-controlled device with a magnetic resonance technique can be applied in many behavioral tasks in mice and rats. To avoid the adverse effects of high radio frequency and to extend the electromagnetic field’s range, this novel technique serves as a helpful tool to modulate the neuronal activity of target neurons in specific brain areas for optogenetic experiments. |
format | Online Article Text |
id | pubmed-7590226 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-75902262020-10-29 A Wireless Magnetic Resonance Device for Optogenetic Applications in an Animal Model Tsai, Arthur C. Huang, Andrew Chih Wei Yu, Ying Hao Kuo, Chii-Shyang Hsu, Chih-Chan Lim, Yeou San Shyu, Bai Chuang Sensors (Basel) Article The currents of optical stimulation devices with tethered or untethered systems have various disadvantages, including optical fiber breakage, disrupted animal movements, heavy batteries carried on heads, and high-frequency electromagnetic impacts. Our novel wireless remote control was developed to address these issues. The novel wireless device uses a magnetic resonance technique to modify the deficits of the conventional magnetic induction or radio-frequency power sources. The present device emits a strong and steady electromagnetic power. It is cheaper than previous versions, and the receiver coil on its head is very light (≦ 1 g). For the present wireless remote-controlled device, the electromagnetic field’s range (i.e., +5 cm and −5 cm of the outside coil) is larger than the range for the magnetic induction and radio-frequency power sources. The present device controls animals’ behavior by the electromagnetic field’s effective range via photostimulation. The novel wireless remote-controlled device with a magnetic resonance technique can be applied in many behavioral tasks in mice and rats. To avoid the adverse effects of high radio frequency and to extend the electromagnetic field’s range, this novel technique serves as a helpful tool to modulate the neuronal activity of target neurons in specific brain areas for optogenetic experiments. MDPI 2020-10-16 /pmc/articles/PMC7590226/ /pubmed/33081369 http://dx.doi.org/10.3390/s20205869 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Tsai, Arthur C. Huang, Andrew Chih Wei Yu, Ying Hao Kuo, Chii-Shyang Hsu, Chih-Chan Lim, Yeou San Shyu, Bai Chuang A Wireless Magnetic Resonance Device for Optogenetic Applications in an Animal Model |
title | A Wireless Magnetic Resonance Device for Optogenetic Applications in an Animal Model |
title_full | A Wireless Magnetic Resonance Device for Optogenetic Applications in an Animal Model |
title_fullStr | A Wireless Magnetic Resonance Device for Optogenetic Applications in an Animal Model |
title_full_unstemmed | A Wireless Magnetic Resonance Device for Optogenetic Applications in an Animal Model |
title_short | A Wireless Magnetic Resonance Device for Optogenetic Applications in an Animal Model |
title_sort | wireless magnetic resonance device for optogenetic applications in an animal model |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590226/ https://www.ncbi.nlm.nih.gov/pubmed/33081369 http://dx.doi.org/10.3390/s20205869 |
work_keys_str_mv | AT tsaiarthurc awirelessmagneticresonancedeviceforoptogeneticapplicationsinananimalmodel AT huangandrewchihwei awirelessmagneticresonancedeviceforoptogeneticapplicationsinananimalmodel AT yuyinghao awirelessmagneticresonancedeviceforoptogeneticapplicationsinananimalmodel AT kuochiishyang awirelessmagneticresonancedeviceforoptogeneticapplicationsinananimalmodel AT hsuchihchan awirelessmagneticresonancedeviceforoptogeneticapplicationsinananimalmodel AT limyeousan awirelessmagneticresonancedeviceforoptogeneticapplicationsinananimalmodel AT shyubaichuang awirelessmagneticresonancedeviceforoptogeneticapplicationsinananimalmodel AT tsaiarthurc wirelessmagneticresonancedeviceforoptogeneticapplicationsinananimalmodel AT huangandrewchihwei wirelessmagneticresonancedeviceforoptogeneticapplicationsinananimalmodel AT yuyinghao wirelessmagneticresonancedeviceforoptogeneticapplicationsinananimalmodel AT kuochiishyang wirelessmagneticresonancedeviceforoptogeneticapplicationsinananimalmodel AT hsuchihchan wirelessmagneticresonancedeviceforoptogeneticapplicationsinananimalmodel AT limyeousan wirelessmagneticresonancedeviceforoptogeneticapplicationsinananimalmodel AT shyubaichuang wirelessmagneticresonancedeviceforoptogeneticapplicationsinananimalmodel |