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High‐sugar diet intake, physical activity, and gut microbiota crosstalk: Implications for obesity in rats
This study aims to evaluate the effect of long‐term high‐sugar diet (HSD) intake and regular physical activity on gut microbiota as well as its health impact. Weaned male Wistar rats were fed with standard chow diet (SSD) or HSD ad libitum and subjected or not to regular swimming training with a wor...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590324/ https://www.ncbi.nlm.nih.gov/pubmed/33133570 http://dx.doi.org/10.1002/fsn3.1842 |
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author | de Oliveira Neves, Viviano Gomes de Oliveira, Daiane Teixeira Oliveira, Deborah Campos Oliveira Perucci, Luiza dos Santos, Talita Adriana Pereira da Costa Fernandes, Isabela de Sousa, Graziele Galdino Barboza, Natália Rocha Guerra‐Sá, Renata |
author_facet | de Oliveira Neves, Viviano Gomes de Oliveira, Daiane Teixeira Oliveira, Deborah Campos Oliveira Perucci, Luiza dos Santos, Talita Adriana Pereira da Costa Fernandes, Isabela de Sousa, Graziele Galdino Barboza, Natália Rocha Guerra‐Sá, Renata |
author_sort | de Oliveira Neves, Viviano Gomes |
collection | PubMed |
description | This study aims to evaluate the effect of long‐term high‐sugar diet (HSD) intake and regular physical activity on gut microbiota as well as its health impact. Weaned male Wistar rats were fed with standard chow diet (SSD) or HSD ad libitum and subjected or not to regular swimming training with a workload (2% of body weight) for 15 weeks. Feces samples were used on microbiome analysis using 16S rRNA amplicon sequencing. HSD increased body mass, adipose cushions, and the serum levels of triglycerides and VLDL, also changed the bacteria taxons associated with metabolic disorders (increase taxons belonging to Proteobacteria phylum and decrease Pediococcus genus); the swim training reverted these changes. SSD intake increased the abundance of bacteria associated with metabolization of dietary fiber. Training in association with SSD consumption beneficially modulated the microbiota, increasing the Bacteroidetes, Bacteroidaceae, Porphyromonadaceae, Parabacteroides, and Lactobacillaceae, and decreasing the Firmicute/Bacteroidetes ratio; training was not able to maintain this profile in animals SHD‐fed. Physical training modulates the gut microbiota reversing the obesogenic response caused by SHD. However, training itself is not efficient for up‐regulating the probiotic bacteria in comparison to its association with a balanced diet. |
format | Online Article Text |
id | pubmed-7590324 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-75903242020-10-30 High‐sugar diet intake, physical activity, and gut microbiota crosstalk: Implications for obesity in rats de Oliveira Neves, Viviano Gomes de Oliveira, Daiane Teixeira Oliveira, Deborah Campos Oliveira Perucci, Luiza dos Santos, Talita Adriana Pereira da Costa Fernandes, Isabela de Sousa, Graziele Galdino Barboza, Natália Rocha Guerra‐Sá, Renata Food Sci Nutr Original Research This study aims to evaluate the effect of long‐term high‐sugar diet (HSD) intake and regular physical activity on gut microbiota as well as its health impact. Weaned male Wistar rats were fed with standard chow diet (SSD) or HSD ad libitum and subjected or not to regular swimming training with a workload (2% of body weight) for 15 weeks. Feces samples were used on microbiome analysis using 16S rRNA amplicon sequencing. HSD increased body mass, adipose cushions, and the serum levels of triglycerides and VLDL, also changed the bacteria taxons associated with metabolic disorders (increase taxons belonging to Proteobacteria phylum and decrease Pediococcus genus); the swim training reverted these changes. SSD intake increased the abundance of bacteria associated with metabolization of dietary fiber. Training in association with SSD consumption beneficially modulated the microbiota, increasing the Bacteroidetes, Bacteroidaceae, Porphyromonadaceae, Parabacteroides, and Lactobacillaceae, and decreasing the Firmicute/Bacteroidetes ratio; training was not able to maintain this profile in animals SHD‐fed. Physical training modulates the gut microbiota reversing the obesogenic response caused by SHD. However, training itself is not efficient for up‐regulating the probiotic bacteria in comparison to its association with a balanced diet. John Wiley and Sons Inc. 2020-09-09 /pmc/articles/PMC7590324/ /pubmed/33133570 http://dx.doi.org/10.1002/fsn3.1842 Text en © 2020 The Authors. Food Science & Nutrition published by Wiley Periodicals LLC. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Research de Oliveira Neves, Viviano Gomes de Oliveira, Daiane Teixeira Oliveira, Deborah Campos Oliveira Perucci, Luiza dos Santos, Talita Adriana Pereira da Costa Fernandes, Isabela de Sousa, Graziele Galdino Barboza, Natália Rocha Guerra‐Sá, Renata High‐sugar diet intake, physical activity, and gut microbiota crosstalk: Implications for obesity in rats |
title | High‐sugar diet intake, physical activity, and gut microbiota crosstalk: Implications for obesity in rats |
title_full | High‐sugar diet intake, physical activity, and gut microbiota crosstalk: Implications for obesity in rats |
title_fullStr | High‐sugar diet intake, physical activity, and gut microbiota crosstalk: Implications for obesity in rats |
title_full_unstemmed | High‐sugar diet intake, physical activity, and gut microbiota crosstalk: Implications for obesity in rats |
title_short | High‐sugar diet intake, physical activity, and gut microbiota crosstalk: Implications for obesity in rats |
title_sort | high‐sugar diet intake, physical activity, and gut microbiota crosstalk: implications for obesity in rats |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590324/ https://www.ncbi.nlm.nih.gov/pubmed/33133570 http://dx.doi.org/10.1002/fsn3.1842 |
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