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Extracellular tyrosyl‐tRNA synthetase cleaved by plasma proteinases and stored in platelet α‐granules: Potential role in monocyte activation

BACKGROUND: Tyrosyl‐tRNA synthetase (YRS) belongs to the family of enzymes that catalyzes the tRNA aminoacylation reaction for protein synthesis, and it has been recently shown to exert noncanonical functions. Although database results indicate extremely low levels of YRS mRNA in platelets, YRS prot...

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Detalles Bibliográficos
Autores principales: Won, Eric, Morodomi, Yosuke, Kanaji, Sachiko, Shapiro, Ryan, Vo, My‐Nuong, Orje, Jennifer N., Thornburg, Courtney D., Yang, Xiang‐Lei, Ruggeri, Zaverio M., Schimmel, Paul, Kanaji, Taisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590329/
https://www.ncbi.nlm.nih.gov/pubmed/33134783
http://dx.doi.org/10.1002/rth2.12429