Differential kynurenine pathway metabolism in highly metastatic aggressive breast cancer subtypes: beyond IDO1-induced immunosuppression

BACKGROUND: Immunotherapy has recently been proposed as a promising treatment to stop breast cancer (BrCa) progression and metastasis. However, there has been limited success in the treatment of BrCa with immune checkpoint inhibitors. This implies that BrCa tumors have other mechanisms to escape imm...

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Detalles Bibliográficos
Autores principales: Heng, Benjamin, Bilgin, Ayse A., Lovejoy, David B., Tan, Vanessa X., Milioli, Heloisa H., Gluch, Laurence, Bustamante, Sonia, Sabaretnam, Tharani, Moscato, Pablo, Lim, Chai K., Guillemin, Gilles J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590459/
https://www.ncbi.nlm.nih.gov/pubmed/33109232
http://dx.doi.org/10.1186/s13058-020-01351-1

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