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Longevity, clonal relationship, and transcriptional program of celiac disease–specific plasma cells

Disease-specific plasma cells (PCs) reactive with transglutaminase 2 (TG2) or deamidated gluten peptides (DGPs) are abundant in celiac disease (CeD) gut lesions. Their contribution toward CeD pathogenesis is unclear. We assessed expression of markers associated with PC longevity in 15 untreated and...

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Detalles Bibliográficos
Autores principales: Lindeman, Ida, Zhou, Chunyan, Eggesbø, Linn M., Miao, Zhichao, Polak, Justyna, Lundin, Knut E.A., Jahnsen, Jørgen, Qiao, Shuo-Wang, Iversen, Rasmus, Sollid, Ludvig M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590513/
https://www.ncbi.nlm.nih.gov/pubmed/33095260
http://dx.doi.org/10.1084/jem.20200852