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Suppressive effects of plumbagin on the growth of human bladder cancer cells via PI3K/AKT/mTOR signaling pathways and EMT
BACKGROUND: Novel chemotherapeutic drugs with good anti-tumor activity are of pressing need for bladder cancer treatment. In this study, plumbagin (PL), a natural plant-derived drug extracted from Chinese herbals, was identified as a promising candidate for human bladder cancer (BCa) chemotherapy. M...
Autores principales: | Zhang, Renjie, Wang, Zijian, You, Wenjie, Zhou, Fengfang, Guo, Zicheng, Qian, Kaiyu, Xiao, Yu, Wang, Xinghuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590591/ https://www.ncbi.nlm.nih.gov/pubmed/33117085 http://dx.doi.org/10.1186/s12935-020-01607-y |
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