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Tyrosine kinase inhibitors for solid tumors in the past 20 years (2001–2020)
Tyrosine kinases are implicated in tumorigenesis and progression, and have emerged as major targets for drug discovery. Tyrosine kinase inhibitors (TKIs) inhibit corresponding kinases from phosphorylating tyrosine residues of their substrates and then block the activation of downstream signaling pat...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590700/ https://www.ncbi.nlm.nih.gov/pubmed/33109256 http://dx.doi.org/10.1186/s13045-020-00977-0 |