Cargando…
A mathematical model of the metastatic bottleneck predicts patient outcome and response to cancer treatment
Metastases are the main reason for cancer-related deaths. Initiation of metastases, where newly seeded tumor cells expand into colonies, presents a tremendous bottleneck to metastasis formation. Despite its importance, a quantitative description of metastasis initiation and its clinical implications...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591057/ https://www.ncbi.nlm.nih.gov/pubmed/33006977 http://dx.doi.org/10.1371/journal.pcbi.1008056 |