Cargando…

Drosophila Caliban preserves intestinal homeostasis and lifespan through regulating mitochondrial dynamics and redox state in enterocytes

Precise regulation of stem cell activity is crucial for tissue homeostasis. In Drosophila, intestinal stem cells (ISCs) maintain the midgut epithelium and respond to oxidative challenges. However, the connection between intestinal homeostasis and redox signaling remains obscure. Here we find that Ca...

Descripción completa

Detalles Bibliográficos
Autores principales: Dai, Zhaoxia, Li, Dong, Du, Xiao, Ge, Ying, Hursh, Deborah A., Bi, Xiaolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591072/
https://www.ncbi.nlm.nih.gov/pubmed/33057338
http://dx.doi.org/10.1371/journal.pgen.1009140