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Longer Distance From Dialysis Facility to Transplant Center Is Associated With Lower Access to Kidney Transplantation

Rates of kidney transplantation vary substantially across dialysis facilities in the United States. Whether distance between the dialysis facility and transplant center associates with variations in transplantation rates has not been examined. METHODS. We performed a retrospective study of adults tr...

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Autores principales: Whelan, Adrian M., Johansen, Kirsten L., McCulloch, Charles E., Adelmann, Dieter, Niemann, Claus U., Roll, Garrett R., Siyahian, Salpi, Grimes, Barbara, Ku, Elaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591118/
https://www.ncbi.nlm.nih.gov/pubmed/33134482
http://dx.doi.org/10.1097/TXD.0000000000001048
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author Whelan, Adrian M.
Johansen, Kirsten L.
McCulloch, Charles E.
Adelmann, Dieter
Niemann, Claus U.
Roll, Garrett R.
Siyahian, Salpi
Grimes, Barbara
Ku, Elaine
author_facet Whelan, Adrian M.
Johansen, Kirsten L.
McCulloch, Charles E.
Adelmann, Dieter
Niemann, Claus U.
Roll, Garrett R.
Siyahian, Salpi
Grimes, Barbara
Ku, Elaine
author_sort Whelan, Adrian M.
collection PubMed
description Rates of kidney transplantation vary substantially across dialysis facilities in the United States. Whether distance between the dialysis facility and transplant center associates with variations in transplantation rates has not been examined. METHODS. We performed a retrospective study of adults treated with dialysis between 2005 and 2015, according to the US Renal Data System. We examined the association between distance from dialysis facility to transplant center and time to kidney transplantation (primary outcome) and waitlist registration (secondary outcome) using Fine-Gray models. We also performed sensitivity analyses using the distance from each patient’s dialysis facility to the nearest transplant center as the predictor so that patients who were never registered on the waitlist (and therefore would not have a transplant center) could be included. RESULTS. In total, 178 885 waitlisted patients were included for our primary analysis. As distance between dialysis facility and transplant center increased, lower hazard of transplantation (subhazard ratio [HR], 0.92; 95% confidence interval [CI], 0.91-0.94, if distance was 10 to <50 miles; sub-HR, 0.90; 95% CI, 0.88-0.92, if distance ≥50 miles compared with <10 miles) was noted. We also found a weak association between longer distance and hazard of waitlist registration (sub-HR, 0.96; 95% CI, 0.94-0.97, if distance was ≥50 miles versus <10 miles). Findings were similar in sensitivity analyses using distance between dialysis facility and the nearest transplant center (N = 1 149 721). CONCLUSIONS. Patients receiving dialysis in facilities located further away from transplant centers have lower hazard of kidney transplantation. Developing strategies to address barriers to transplantation in patients receiving dialysis at facilities located far away from a transplant center may help improve disparities in transplantation rates.
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spelling pubmed-75911182020-10-29 Longer Distance From Dialysis Facility to Transplant Center Is Associated With Lower Access to Kidney Transplantation Whelan, Adrian M. Johansen, Kirsten L. McCulloch, Charles E. Adelmann, Dieter Niemann, Claus U. Roll, Garrett R. Siyahian, Salpi Grimes, Barbara Ku, Elaine Transplant Direct Kidney Transplantation Rates of kidney transplantation vary substantially across dialysis facilities in the United States. Whether distance between the dialysis facility and transplant center associates with variations in transplantation rates has not been examined. METHODS. We performed a retrospective study of adults treated with dialysis between 2005 and 2015, according to the US Renal Data System. We examined the association between distance from dialysis facility to transplant center and time to kidney transplantation (primary outcome) and waitlist registration (secondary outcome) using Fine-Gray models. We also performed sensitivity analyses using the distance from each patient’s dialysis facility to the nearest transplant center as the predictor so that patients who were never registered on the waitlist (and therefore would not have a transplant center) could be included. RESULTS. In total, 178 885 waitlisted patients were included for our primary analysis. As distance between dialysis facility and transplant center increased, lower hazard of transplantation (subhazard ratio [HR], 0.92; 95% confidence interval [CI], 0.91-0.94, if distance was 10 to <50 miles; sub-HR, 0.90; 95% CI, 0.88-0.92, if distance ≥50 miles compared with <10 miles) was noted. We also found a weak association between longer distance and hazard of waitlist registration (sub-HR, 0.96; 95% CI, 0.94-0.97, if distance was ≥50 miles versus <10 miles). Findings were similar in sensitivity analyses using distance between dialysis facility and the nearest transplant center (N = 1 149 721). CONCLUSIONS. Patients receiving dialysis in facilities located further away from transplant centers have lower hazard of kidney transplantation. Developing strategies to address barriers to transplantation in patients receiving dialysis at facilities located far away from a transplant center may help improve disparities in transplantation rates. Lippincott Williams & Wilkins 2020-09-17 /pmc/articles/PMC7591118/ /pubmed/33134482 http://dx.doi.org/10.1097/TXD.0000000000001048 Text en Copyright © 2020 The Author(s). Transplantation Direct. Published by Wolters Kluwer Health, Inc. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Kidney Transplantation
Whelan, Adrian M.
Johansen, Kirsten L.
McCulloch, Charles E.
Adelmann, Dieter
Niemann, Claus U.
Roll, Garrett R.
Siyahian, Salpi
Grimes, Barbara
Ku, Elaine
Longer Distance From Dialysis Facility to Transplant Center Is Associated With Lower Access to Kidney Transplantation
title Longer Distance From Dialysis Facility to Transplant Center Is Associated With Lower Access to Kidney Transplantation
title_full Longer Distance From Dialysis Facility to Transplant Center Is Associated With Lower Access to Kidney Transplantation
title_fullStr Longer Distance From Dialysis Facility to Transplant Center Is Associated With Lower Access to Kidney Transplantation
title_full_unstemmed Longer Distance From Dialysis Facility to Transplant Center Is Associated With Lower Access to Kidney Transplantation
title_short Longer Distance From Dialysis Facility to Transplant Center Is Associated With Lower Access to Kidney Transplantation
title_sort longer distance from dialysis facility to transplant center is associated with lower access to kidney transplantation
topic Kidney Transplantation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591118/
https://www.ncbi.nlm.nih.gov/pubmed/33134482
http://dx.doi.org/10.1097/TXD.0000000000001048
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