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A qPCR Method for AAV Genome Titer with ddPCR-Level of Accuracy and Precision

Recombinant adeno-associated virus (rAAV) is one of the main vectors used in gene therapy. An accurate genome titer is not only critical for clinical dosing, but also a prerequisite for many analytical assays for AAV product characterization. AAV genome titer is traditionally determined by qPCR; how...

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Detalles Bibliográficos
Autores principales:	Wang, Yu, Menon, Namrata, Shen, Shen, Feschenko, Marina, Bergelson, Svetlana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591332/ https://www.ncbi.nlm.nih.gov/pubmed/33145370 http://dx.doi.org/10.1016/j.omtm.2020.09.017

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