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Emergency laparotomy in the older patient: factors predictive of 12-month mortality—Salford-POPS-GS. An observational study

INTRODUCTION: Although high rates of in-hospital mortality have been described in older patients undergoing emergency laparotomy (EL), less is known about longer-term outcomes in this population. We describe factors present at the time of hospital admission that influence 12-month survival in older...

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Autores principales: Vilches-Moraga, Arturo, Rowley, Mollie, Fox, Jenny, Khan, Haroon, Paracha, Areej, Price, Angeline, Pearce, Lyndsay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591437/
https://www.ncbi.nlm.nih.gov/pubmed/32449105
http://dx.doi.org/10.1007/s40520-020-01578-0
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author Vilches-Moraga, Arturo
Rowley, Mollie
Fox, Jenny
Khan, Haroon
Paracha, Areej
Price, Angeline
Pearce, Lyndsay
author_facet Vilches-Moraga, Arturo
Rowley, Mollie
Fox, Jenny
Khan, Haroon
Paracha, Areej
Price, Angeline
Pearce, Lyndsay
author_sort Vilches-Moraga, Arturo
collection PubMed
description INTRODUCTION: Although high rates of in-hospital mortality have been described in older patients undergoing emergency laparotomy (EL), less is known about longer-term outcomes in this population. We describe factors present at the time of hospital admission that influence 12-month survival in older patients. METHODS: Observational study of patients aged 75 years and over, who underwent EL at our hospital between 8th September 2014 and 30th March 2017. RESULTS: 113 patients were included. Average age was 81.9 ± 4.7 years, female predominance (60/113), 3 (2.6%) lived in a care home, 103 (91.2%) and 79 (69.1%) were independent of personal and instrumental activities of daily living (ADLs) and 8 (7.1%) had cognitive impairment. Median length of stay was 16 days ± 29.9 (0–269); in-hospital mortality 22.1% (25/113), post-operative 30-day, 90-day and 12-month mortality rates 19.5% (22), 24.8% (28) and 38.9% (44). 30-day and 12-month readmission rates 5.7% (5/88) and 40.9% (36). 12-month readmission was higher in frail patients, using the Clinical Frailty Scale (CFS) score (64% 5–8 vs 31.7% 1–4, p = 0.006). Dependency for personal ADLs (6/10 (60%) dependent vs. 38/103 (36.8%) independent, p = 0.119) and cognitive impairment (5/8 (62.5%) impaired vs. 39/105 (37.1%) no impairment, p = 0.116) showed a trend towards higher 12-month mortality. On multivariate analysis, 12-month mortality was strongly associated with CFS 5–9 (HR 5.0403 (95% CI 1.719–16.982) and ASA classes III–V (HR 2.704 95% CI 1.032–7.081). CONCLUSION: Frailty and high ASA class predict increased mortality at 12 months after emergency laparotomy. We advocate early engagement of multi-professional teams experienced in perioperative care of older patients.
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spelling pubmed-75914372020-10-29 Emergency laparotomy in the older patient: factors predictive of 12-month mortality—Salford-POPS-GS. An observational study Vilches-Moraga, Arturo Rowley, Mollie Fox, Jenny Khan, Haroon Paracha, Areej Price, Angeline Pearce, Lyndsay Aging Clin Exp Res Original Article INTRODUCTION: Although high rates of in-hospital mortality have been described in older patients undergoing emergency laparotomy (EL), less is known about longer-term outcomes in this population. We describe factors present at the time of hospital admission that influence 12-month survival in older patients. METHODS: Observational study of patients aged 75 years and over, who underwent EL at our hospital between 8th September 2014 and 30th March 2017. RESULTS: 113 patients were included. Average age was 81.9 ± 4.7 years, female predominance (60/113), 3 (2.6%) lived in a care home, 103 (91.2%) and 79 (69.1%) were independent of personal and instrumental activities of daily living (ADLs) and 8 (7.1%) had cognitive impairment. Median length of stay was 16 days ± 29.9 (0–269); in-hospital mortality 22.1% (25/113), post-operative 30-day, 90-day and 12-month mortality rates 19.5% (22), 24.8% (28) and 38.9% (44). 30-day and 12-month readmission rates 5.7% (5/88) and 40.9% (36). 12-month readmission was higher in frail patients, using the Clinical Frailty Scale (CFS) score (64% 5–8 vs 31.7% 1–4, p = 0.006). Dependency for personal ADLs (6/10 (60%) dependent vs. 38/103 (36.8%) independent, p = 0.119) and cognitive impairment (5/8 (62.5%) impaired vs. 39/105 (37.1%) no impairment, p = 0.116) showed a trend towards higher 12-month mortality. On multivariate analysis, 12-month mortality was strongly associated with CFS 5–9 (HR 5.0403 (95% CI 1.719–16.982) and ASA classes III–V (HR 2.704 95% CI 1.032–7.081). CONCLUSION: Frailty and high ASA class predict increased mortality at 12 months after emergency laparotomy. We advocate early engagement of multi-professional teams experienced in perioperative care of older patients. Springer International Publishing 2020-05-24 2020 /pmc/articles/PMC7591437/ /pubmed/32449105 http://dx.doi.org/10.1007/s40520-020-01578-0 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Original Article
Vilches-Moraga, Arturo
Rowley, Mollie
Fox, Jenny
Khan, Haroon
Paracha, Areej
Price, Angeline
Pearce, Lyndsay
Emergency laparotomy in the older patient: factors predictive of 12-month mortality—Salford-POPS-GS. An observational study
title Emergency laparotomy in the older patient: factors predictive of 12-month mortality—Salford-POPS-GS. An observational study
title_full Emergency laparotomy in the older patient: factors predictive of 12-month mortality—Salford-POPS-GS. An observational study
title_fullStr Emergency laparotomy in the older patient: factors predictive of 12-month mortality—Salford-POPS-GS. An observational study
title_full_unstemmed Emergency laparotomy in the older patient: factors predictive of 12-month mortality—Salford-POPS-GS. An observational study
title_short Emergency laparotomy in the older patient: factors predictive of 12-month mortality—Salford-POPS-GS. An observational study
title_sort emergency laparotomy in the older patient: factors predictive of 12-month mortality—salford-pops-gs. an observational study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591437/
https://www.ncbi.nlm.nih.gov/pubmed/32449105
http://dx.doi.org/10.1007/s40520-020-01578-0
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