Cargando…

Challenges of Developing Novel Vaccines With Particular Global Health Importance

Six of the top ten leading causes of death in low resource settings could potentially be prevented by vaccination. Development of vaccines for individuals in these populations is difficult because of the biological complexity of the prevalent pathogens and the challenges inherent to development of a...

Descripción completa

Detalles Bibliográficos
Autor principal: Heaton, Penny M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591467/
https://www.ncbi.nlm.nih.gov/pubmed/33162972
http://dx.doi.org/10.3389/fimmu.2020.517290
_version_ 1783601000566751232
author Heaton, Penny M.
author_facet Heaton, Penny M.
author_sort Heaton, Penny M.
collection PubMed
description Six of the top ten leading causes of death in low resource settings could potentially be prevented by vaccination. Development of vaccines for individuals in these populations is difficult because of the biological complexity of the prevalent pathogens and the challenges inherent to development of any vaccine. This review discusses those challenges and promising advances to address them and highlights recent progress in development of vaccines against several pathogens of interest.
format Online
Article
Text
id pubmed-7591467
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-75914672020-11-05 Challenges of Developing Novel Vaccines With Particular Global Health Importance Heaton, Penny M. Front Immunol Immunology Six of the top ten leading causes of death in low resource settings could potentially be prevented by vaccination. Development of vaccines for individuals in these populations is difficult because of the biological complexity of the prevalent pathogens and the challenges inherent to development of any vaccine. This review discusses those challenges and promising advances to address them and highlights recent progress in development of vaccines against several pathogens of interest. Frontiers Media S.A. 2020-10-14 /pmc/articles/PMC7591467/ /pubmed/33162972 http://dx.doi.org/10.3389/fimmu.2020.517290 Text en Copyright © 2020 Heaton. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Immunology
Heaton, Penny M.
Challenges of Developing Novel Vaccines With Particular Global Health Importance
title Challenges of Developing Novel Vaccines With Particular Global Health Importance
title_full Challenges of Developing Novel Vaccines With Particular Global Health Importance
title_fullStr Challenges of Developing Novel Vaccines With Particular Global Health Importance
title_full_unstemmed Challenges of Developing Novel Vaccines With Particular Global Health Importance
title_short Challenges of Developing Novel Vaccines With Particular Global Health Importance
title_sort challenges of developing novel vaccines with particular global health importance
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591467/
https://www.ncbi.nlm.nih.gov/pubmed/33162972
http://dx.doi.org/10.3389/fimmu.2020.517290
work_keys_str_mv AT heatonpennym challengesofdevelopingnovelvaccineswithparticularglobalhealthimportance