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Akt isoform-specific effects on thyroid cancer development and progression in a murine thyroid cancer model

The Akt family is comprised of three unique homologous proteins with isoform-specific effects, but isoform-specific in vivo data are limited in follicular thyroid cancer (FTC), a PI3 kinase-driven tumor. Prior studies demonstrated that PI3K/Akt signaling is important in thyroid hormone receptor β(PV...

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Detalles Bibliográficos
Autores principales:	Saji, Motoyasu, Kim, Caroline S., Wang, Chaojie, Zhang, Xiaoli, Khanal, Tilak, Coombes, Kevin, La Perle, Krista, Cheng, Sheue-Yann, Tsichlis, Philip N., Ringel, Matthew D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591514/ https://www.ncbi.nlm.nih.gov/pubmed/33110146 http://dx.doi.org/10.1038/s41598-020-75529-0

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