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Increased estrogen to androgen ratio enhances immunoglobulin levels and impairs B cell function in male mice
Sex steroids, such as estrogens and androgens, are important regulators of the humoral immune response. Studies in female mice have demonstrated that alteration of circulating estrogen concentration regulates antibody-mediated immunity. As males have normally little endogenous estrogen, we hypothesi...
Autores principales: | Aguilar-Pimentel, Juan Antonio, Cho, Yi-Li, Gerlini, Raffaele, Calzada-Wack, Julia, Wimmer, Maria, Mayer-Kuckuk, Philipp, Adler, Thure, Schmidt-Weber, Carsten B., Busch, Dirk H., Fuchs, Helmut, Gailus-Durner, Valérie, Ollert, Markus, Hrabě de Angelis, Martin, Ohlsson, Claes, Poutanen, Matti, Teperino, Raffaele, Strauss, Leena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591566/ https://www.ncbi.nlm.nih.gov/pubmed/33110090 http://dx.doi.org/10.1038/s41598-020-75059-9 |
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