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Increased estrogen to androgen ratio enhances immunoglobulin levels and impairs B cell function in male mice

Sex steroids, such as estrogens and androgens, are important regulators of the humoral immune response. Studies in female mice have demonstrated that alteration of circulating estrogen concentration regulates antibody-mediated immunity. As males have normally little endogenous estrogen, we hypothesi...

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Detalles Bibliográficos
Autores principales: Aguilar-Pimentel, Juan Antonio, Cho, Yi-Li, Gerlini, Raffaele, Calzada-Wack, Julia, Wimmer, Maria, Mayer-Kuckuk, Philipp, Adler, Thure, Schmidt-Weber, Carsten B., Busch, Dirk H., Fuchs, Helmut, Gailus-Durner, Valérie, Ollert, Markus, Hrabě de Angelis, Martin, Ohlsson, Claes, Poutanen, Matti, Teperino, Raffaele, Strauss, Leena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591566/
https://www.ncbi.nlm.nih.gov/pubmed/33110090
http://dx.doi.org/10.1038/s41598-020-75059-9

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