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Gout in the Chest Misdiagnosed as Ankylosing Spondylitis

Gout is a crystal-related joint disease caused by single sodium urate deposition in the joints or in soft tissues. In recent years, the incidence of gout has increased, but cases of urate crystals deposited in the chest–ribs are rare. Here, we describe a 39-year-old man who complained of frequent pa...

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Autores principales: Xue, Wenjing, Zhang, Shengkai, Wang, Qinqin, Que, Wenzhong, Xu, Shanghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591584/
https://www.ncbi.nlm.nih.gov/pubmed/33154973
http://dx.doi.org/10.3389/fmed.2020.582444
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author Xue, Wenjing
Zhang, Shengkai
Wang, Qinqin
Que, Wenzhong
Xu, Shanghua
author_facet Xue, Wenjing
Zhang, Shengkai
Wang, Qinqin
Que, Wenzhong
Xu, Shanghua
author_sort Xue, Wenjing
collection PubMed
description Gout is a crystal-related joint disease caused by single sodium urate deposition in the joints or in soft tissues. In recent years, the incidence of gout has increased, but cases of urate crystals deposited in the chest–ribs are rare. Here, we describe a 39-year-old man who complained of frequent pain and a feeling of tightness in chest–ribs and was misdiagnosed as ankylosing spondylitis. In addition, treatment with non-steroidal anti-inflammatory drugs (NSAIDs) and etanercept for 6 months showed no improvement, which confirmed the misdiagnosis. After physical examination, blood examination, and dual-energy CT examination, the patient was diagnosed with gout and received 50 mg benzbromarone once a day with treatment of low serum uric acid. In conclusion, gout in the chest and ribs is an unusual manifestation and has rarely been reported in the literature. This case highlights an important but overlooked history of hyperuricemia in the diagnosis, and dual-energy CT is the preferred method for differential diagnosis of chest–ribs gout.
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spelling pubmed-75915842020-11-04 Gout in the Chest Misdiagnosed as Ankylosing Spondylitis Xue, Wenjing Zhang, Shengkai Wang, Qinqin Que, Wenzhong Xu, Shanghua Front Med (Lausanne) Medicine Gout is a crystal-related joint disease caused by single sodium urate deposition in the joints or in soft tissues. In recent years, the incidence of gout has increased, but cases of urate crystals deposited in the chest–ribs are rare. Here, we describe a 39-year-old man who complained of frequent pain and a feeling of tightness in chest–ribs and was misdiagnosed as ankylosing spondylitis. In addition, treatment with non-steroidal anti-inflammatory drugs (NSAIDs) and etanercept for 6 months showed no improvement, which confirmed the misdiagnosis. After physical examination, blood examination, and dual-energy CT examination, the patient was diagnosed with gout and received 50 mg benzbromarone once a day with treatment of low serum uric acid. In conclusion, gout in the chest and ribs is an unusual manifestation and has rarely been reported in the literature. This case highlights an important but overlooked history of hyperuricemia in the diagnosis, and dual-energy CT is the preferred method for differential diagnosis of chest–ribs gout. Frontiers Media S.A. 2020-10-14 /pmc/articles/PMC7591584/ /pubmed/33154973 http://dx.doi.org/10.3389/fmed.2020.582444 Text en Copyright © 2020 Xue, Zhang, Wang, Que and Xu. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Xue, Wenjing
Zhang, Shengkai
Wang, Qinqin
Que, Wenzhong
Xu, Shanghua
Gout in the Chest Misdiagnosed as Ankylosing Spondylitis
title Gout in the Chest Misdiagnosed as Ankylosing Spondylitis
title_full Gout in the Chest Misdiagnosed as Ankylosing Spondylitis
title_fullStr Gout in the Chest Misdiagnosed as Ankylosing Spondylitis
title_full_unstemmed Gout in the Chest Misdiagnosed as Ankylosing Spondylitis
title_short Gout in the Chest Misdiagnosed as Ankylosing Spondylitis
title_sort gout in the chest misdiagnosed as ankylosing spondylitis
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591584/
https://www.ncbi.nlm.nih.gov/pubmed/33154973
http://dx.doi.org/10.3389/fmed.2020.582444
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