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Polymorphisms in STING Affect Human Innate Immune Responses to Poxviruses

We conducted a large genome-wide association study (GWAS) of the immune responses to primary smallpox vaccination in a combined cohort of 1,653 subjects. We did not observe any polymorphisms associated with standard vaccine response outcomes (e.g., neutralizing antibody, T cell ELISPOT response, or...

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Detalles Bibliográficos
Autores principales: Kennedy, Richard B., Haralambieva, Iana H., Ovsyannikova, Inna G., Voigt, Emily A., Larrabee, Beth R., Schaid, Daniel J., Zimmermann, Michael T., Oberg, Ann L., Poland, Gregory A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591719/
https://www.ncbi.nlm.nih.gov/pubmed/33154747
http://dx.doi.org/10.3389/fimmu.2020.567348