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Fast kinetics of environmentally induced α-synuclein aggregation mediated by structural alteration in NAC region and result in structure dependent cytotoxicity

Aggregation of α-synuclein (α-syn) is associated with the manifestation of various pathogenic synucleinopathies, including Parkinson’s disease attributed to both genetic and environmental stress factors. The initial events triggering α-syn aggregation and disease initiation due to environmental stre...

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Detalles Bibliográficos
Autores principales:	Srivastava, Tulika, Raj, Ritu, Dubey, Amit, Kumar, Dinesh, Chaturvedi, Rajnish K., Sharma, Sandeep K., Priya, Smriti
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591854/ https://www.ncbi.nlm.nih.gov/pubmed/33110167 http://dx.doi.org/10.1038/s41598-020-75361-6

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