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Developments in biosensors for CoV detection and future trends
This review summarizes the state of art of biosensor technology for Coronavirus (CoV) detection, the current challenges and the future perspectives. Three categories of affinity-based biosensors (ABBs) have been developed, depending on their transduction mechanism, namely electrochemical, optical an...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Elsevier B.V.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591947/ https://www.ncbi.nlm.nih.gov/pubmed/33189015 http://dx.doi.org/10.1016/j.bios.2020.112777 |
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author | Antiochia, Riccarda |
author_facet | Antiochia, Riccarda |
author_sort | Antiochia, Riccarda |
collection | PubMed |
description | This review summarizes the state of art of biosensor technology for Coronavirus (CoV) detection, the current challenges and the future perspectives. Three categories of affinity-based biosensors (ABBs) have been developed, depending on their transduction mechanism, namely electrochemical, optical and piezoelectric biosensors. The biorecognition elements include antibodies and DNA, which undergo important non-covalent binding interactions, with the formation of antigen-antibody and ssDNA/oligonucleotide-complementary strand complexes in immuno- and DNA-sensors, respectively. The analytical performances, the advantages and drawbacks of each type of biosensor are highlighted, discussed, and compared to traditional methods. It is hoped that this review will encourage scientists and academics to design and develop new biosensing platforms for point-of-care (POC) diagnostics to manage the coronavirus disease 2019 (COVID-19) pandemic, providing interesting reference for future studies. |
format | Online Article Text |
id | pubmed-7591947 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier B.V. |
record_format | MEDLINE/PubMed |
spelling | pubmed-75919472020-10-28 Developments in biosensors for CoV detection and future trends Antiochia, Riccarda Biosens Bioelectron Article This review summarizes the state of art of biosensor technology for Coronavirus (CoV) detection, the current challenges and the future perspectives. Three categories of affinity-based biosensors (ABBs) have been developed, depending on their transduction mechanism, namely electrochemical, optical and piezoelectric biosensors. The biorecognition elements include antibodies and DNA, which undergo important non-covalent binding interactions, with the formation of antigen-antibody and ssDNA/oligonucleotide-complementary strand complexes in immuno- and DNA-sensors, respectively. The analytical performances, the advantages and drawbacks of each type of biosensor are highlighted, discussed, and compared to traditional methods. It is hoped that this review will encourage scientists and academics to design and develop new biosensing platforms for point-of-care (POC) diagnostics to manage the coronavirus disease 2019 (COVID-19) pandemic, providing interesting reference for future studies. Elsevier B.V. 2021-02-01 2020-10-28 /pmc/articles/PMC7591947/ /pubmed/33189015 http://dx.doi.org/10.1016/j.bios.2020.112777 Text en © 2020 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Antiochia, Riccarda Developments in biosensors for CoV detection and future trends |
title | Developments in biosensors for CoV detection and future trends |
title_full | Developments in biosensors for CoV detection and future trends |
title_fullStr | Developments in biosensors for CoV detection and future trends |
title_full_unstemmed | Developments in biosensors for CoV detection and future trends |
title_short | Developments in biosensors for CoV detection and future trends |
title_sort | developments in biosensors for cov detection and future trends |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591947/ https://www.ncbi.nlm.nih.gov/pubmed/33189015 http://dx.doi.org/10.1016/j.bios.2020.112777 |
work_keys_str_mv | AT antiochiariccarda developmentsinbiosensorsforcovdetectionandfuturetrends |