Orosomucoid 1 Attenuates Doxorubicin-Induced Oxidative Stress and Apoptosis in Cardiomyocytes via Nrf2 Signaling

Doxorubicin (DOX) is an effective anticancer drug, but its therapeutic use is limited by its cardiotoxicity. The principal mechanisms of DOX-induced cardiotoxicity are oxidative stress and apoptosis in cardiomyocytes. Orosomucoid 1 (ORM1), an acute-phase protein, plays important roles in inflammatio...

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Detalles Bibliográficos
Autores principales: Cheng, Xiaoli, Liu, Dan, Xing, Ruinan, Song, Haixu, Tian, Xiaoxiang, Yan, Chenghui, Han, Yaling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591952/
https://www.ncbi.nlm.nih.gov/pubmed/33134382
http://dx.doi.org/10.1155/2020/5923572

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