Cargando…

Complete Recovery from COVID-19 Bilateral Pneumonia in an Immunosuppressed Man with Immune-Mediated Necrotizing Myopathy

Immune-mediated necrotizing myopathy (IMNM) is a rare form of idiopathic immune myopathy (IIM) that requires immunotherapies, including immunosuppressive medications, if severe. There is a paucity of data regarding outcomes of patients with immune-mediated polymyositis who continue immunosuppressive...

Descripción completa

Detalles Bibliográficos
Autores principales: Bolig, Thomas C., Abdulaziz, Nada, Schiopu, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591954/
https://www.ncbi.nlm.nih.gov/pubmed/33133718
http://dx.doi.org/10.1155/2020/8886324
_version_ 1783601095944175616
author Bolig, Thomas C.
Abdulaziz, Nada
Schiopu, Elena
author_facet Bolig, Thomas C.
Abdulaziz, Nada
Schiopu, Elena
author_sort Bolig, Thomas C.
collection PubMed
description Immune-mediated necrotizing myopathy (IMNM) is a rare form of idiopathic immune myopathy (IIM) that requires immunotherapies, including immunosuppressive medications, if severe. There is a paucity of data regarding outcomes of patients with immune-mediated polymyositis who continue immunosuppressive medications during the COVID-19 pandemic. This is the first reported case of COVID-19 in a patient with IMNM. Despite being on two immunotherapies, having risk factors, and having radiographic abnormalities on chest X-ray, the patient had an unremarkable COVID-19 course. He was discharged from the emergency department with a 7-day course of azithromycin and quickly resumed his immunotherapies, but he experienced a flare in his myositis. The 14-week follow-up computed tomography (CT) was negative for residual pneumonitis or fibrosis. More data are needed regarding management and prognosis of patients with connective tissue diseases who become infected with SARS-CoV-2.
format Online
Article
Text
id pubmed-7591954
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-75919542020-10-30 Complete Recovery from COVID-19 Bilateral Pneumonia in an Immunosuppressed Man with Immune-Mediated Necrotizing Myopathy Bolig, Thomas C. Abdulaziz, Nada Schiopu, Elena Case Rep Rheumatol Case Report Immune-mediated necrotizing myopathy (IMNM) is a rare form of idiopathic immune myopathy (IIM) that requires immunotherapies, including immunosuppressive medications, if severe. There is a paucity of data regarding outcomes of patients with immune-mediated polymyositis who continue immunosuppressive medications during the COVID-19 pandemic. This is the first reported case of COVID-19 in a patient with IMNM. Despite being on two immunotherapies, having risk factors, and having radiographic abnormalities on chest X-ray, the patient had an unremarkable COVID-19 course. He was discharged from the emergency department with a 7-day course of azithromycin and quickly resumed his immunotherapies, but he experienced a flare in his myositis. The 14-week follow-up computed tomography (CT) was negative for residual pneumonitis or fibrosis. More data are needed regarding management and prognosis of patients with connective tissue diseases who become infected with SARS-CoV-2. Hindawi 2020-10-21 /pmc/articles/PMC7591954/ /pubmed/33133718 http://dx.doi.org/10.1155/2020/8886324 Text en Copyright © 2020 Thomas C. Bolig et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Bolig, Thomas C.
Abdulaziz, Nada
Schiopu, Elena
Complete Recovery from COVID-19 Bilateral Pneumonia in an Immunosuppressed Man with Immune-Mediated Necrotizing Myopathy
title Complete Recovery from COVID-19 Bilateral Pneumonia in an Immunosuppressed Man with Immune-Mediated Necrotizing Myopathy
title_full Complete Recovery from COVID-19 Bilateral Pneumonia in an Immunosuppressed Man with Immune-Mediated Necrotizing Myopathy
title_fullStr Complete Recovery from COVID-19 Bilateral Pneumonia in an Immunosuppressed Man with Immune-Mediated Necrotizing Myopathy
title_full_unstemmed Complete Recovery from COVID-19 Bilateral Pneumonia in an Immunosuppressed Man with Immune-Mediated Necrotizing Myopathy
title_short Complete Recovery from COVID-19 Bilateral Pneumonia in an Immunosuppressed Man with Immune-Mediated Necrotizing Myopathy
title_sort complete recovery from covid-19 bilateral pneumonia in an immunosuppressed man with immune-mediated necrotizing myopathy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591954/
https://www.ncbi.nlm.nih.gov/pubmed/33133718
http://dx.doi.org/10.1155/2020/8886324
work_keys_str_mv AT boligthomasc completerecoveryfromcovid19bilateralpneumoniainanimmunosuppressedmanwithimmunemediatednecrotizingmyopathy
AT abdulaziznada completerecoveryfromcovid19bilateralpneumoniainanimmunosuppressedmanwithimmunemediatednecrotizingmyopathy
AT schiopuelena completerecoveryfromcovid19bilateralpneumoniainanimmunosuppressedmanwithimmunemediatednecrotizingmyopathy