Cargando…

Network Pharmacology-Based Strategy Reveals the Effects of Hedysarum multijugum Maxim.-Radix Salviae Compound on Oxidative Capacity and Cardiomyocyte Apoptosis in Rats with Diabetic Cardiomyopathy

OBJECTIVE: To explore the effects of the Hedysarum multijugum Maxim.-Radix Salviae compound (Huangqi-Danshen Compound (HDC)) on oxidative capacity and cardiomyocyte apoptosis in rats with diabetic cardiomyopathy by a network pharmacology-based strategy. METHODS: Traditional Chinese Medicine (TCM)@Ta...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Shiying, Yuan, Zhiying, Wu, Huaying, Li, Weiqing, Li, Liang, Huang, Huiyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591987/ https://www.ncbi.nlm.nih.gov/pubmed/33134388 http://dx.doi.org/10.1155/2020/8260703

Ejemplares similares

The Effect of Hedysarum multijugum Maxim.-Chuanxiong rhizoma Compound on Ischemic Stroke: A Research Based on Network and Experimental Pharmacology
por: Yang, Kailin, et al.
Publicado: (2020)

Uncovering the Neuroprotective Effect of Hedysarum multijugum Maxim-Chuanxiong Rhizoma Compound on Cerebral Infarction through Quantitative Proteomics
por: Wang, Guozuo, et al.
Publicado: (2022)

Hedysarum multijugum Maxim treats ulcerative colitis through the PI3K-AKT and TNF signaling pathway according to network pharmacology and molecular docking
por: Zhang, Zihao, et al.
Publicado: (2022)

Exploring the Regulatory Mechanism of Hedysarum Multijugum Maxim.-Chuanxiong Rhizoma Compound on HIF-VEGF Pathway and Cerebral Ischemia-Reperfusion Injury’s Biological Network Based on Systematic Pharmacology
por: Yang, Kailin, et al.
Publicado: (2021)

Integrated Network Pharmacology and Experimental Verification to Explore the Molecular Mechanism of Hedysarum Multijugum Maxim–Curcumae Rhizoma Herb Pair for Treating Non-Small Cell Lung Cancer
por: Hu, Shaopu, et al.
Publicado: (2022)

Pharmacological action of Hedysarum polysaccharides: a review
por: Gao, Xiang, et al.
Publicado: (2023)

Cysteine-Rich Peptide Fingerprinting as a General Method for Herbal Analysis to Differentiate Radix Astragali and Radix Hedysarum
por: Huang, Jiayi, et al.
Publicado: (2019)

Utilizing network pharmacology to explore the underlying mechanism of Radix Salviae in diabetic retinopathy
por: Piao, Chun-Li, et al.
Publicado: (2019)

Exploring the Pharmacological Mechanism of Radix Salvia Miltiorrhizae in the Treatment of Radiation Pneumonia by Using Network Pharmacology
por: Li, Peng, et al.
Publicado: (2021)

The complete chloroplast genome of Corethrodendron multijugum (Fabaceae: Corethrodendron) and phylogenetic analysis
por: Zhang, Li-Jun, et al.
Publicado: (2023)

A network pharmacology-based study on the anti-hepatoma effect of Radix Salviae Miltiorrhizae
por: Luo, Yi, et al.
Publicado: (2019)

Hedysarum Gangeticum in Dysentery
por: Deb, Amrito Lall
Publicado: (1879)

Combined Network Pharmacology and Molecular Docking to Verify the Treatment of Type 2 Diabetes with Pueraria Lobata Radix and Salviae Miltiorrhizae Radix
por: Mao, Jingxin, et al.
Publicado: (2023)

Mechanism of Radix Astragali and Radix Salviae Miltiorrhizae Ameliorates Hypertensive Renal Damage
por: Hou, Guangjian, et al.
Publicado: (2021)

Genotoxicity Evaluation of an Ethanol Extract Mixture of Astragali Radix and Salviae miltiorrhizae Radix
por: Lee, Jin-Seok, et al.
Publicado: (2018)

A Biomedical Investigation of the Hepatoprotective Effect of Radix salviae miltiorrhizae and Network Pharmacology-Based Prediction of the Active Compounds and Molecular Targets
por: Hong, Ming, et al.
Publicado: (2017)

Phytochemicals and biological studies of plants in genus Hedysarum
por: Dong, Yinmao, et al.
Publicado: (2013)

Radix Salvia miltiorrhiza for Ankylosing Spondylitis: Determining Potential Inflammatory Molecular Targets and Mechanism Using Network Pharmacology
por: Fang, Yanyan, et al.
Publicado: (2022)

Mechanism and ingredients prediction of Radix Salviae-Angelicae Sinensis Radix-Lycii Fructus-Rehmanniae Radix Praeparata-Ginkgo Folium for retinitis pigmentosa therapy using network pharmacology and molecular docking analysis
por: Wu, Jiawen, et al.
Publicado: (2023)

A Network Pharmacology Technique to Investigate the Synergistic Mechanisms of Salvia miltiorrhiza and Radix puerariae in Treatment of Cardio-Cerebral Vascular Diseases
por: Ma, Yang, et al.
Publicado: (2020)

Metabolism of Tanshinone IIA, Cryptotanshinone and Tanshinone I from Radix Salvia Miltiorrhiza in Zebrafish
por: Wei, Yingjie, et al.
Publicado: (2012)

Chemical Analysis of the Herbal Medicine Salviae miltiorrhizae Radix et Rhizoma (Danshen)
por: Pang, Hanqing, et al.
Publicado: (2016)

Network Pharmacology and Molecular Docking Analysis on Molecular Targets and Mechanisms of “Chuanxiong Rhizoma: Radix Salviae miltiorrhizae” Herb Couples in the Treatment of Preeclampsia
por: Wei, Jing, et al.
Publicado: (2022)

A Chinese Herbal Preparation Containing Radix Salviae Miltiorrhizae, Radix Notoginseng and Borneolum Syntheticum Reduces Circulating Adhesion Molecules
por: O'Brien, Kylie A., et al.
Publicado: (2011)

Acute and repeated toxicological study of Myelophil, an ethanol extract of a mixture of Astragali Radix and Salviae Miltiorrhizae Radix, in beagle dogs
por: Joung, Jin-Yong, et al.
Publicado: (2019)

Molecular Cytogenetics of Eurasian Species of the Genus Hedysarum L. (Fabaceae)
por: Yurkevich, Olga Yu., et al.
Publicado: (2021)

Synergistic Effects of Danshen (Salvia Miltiorrhizae Radix et Rhizoma) and Sanqi (Notoginseng Radix et Rhizoma) Combination in Angiogenesis Behavior in EAhy 926 Cells
por: Zhou, Xian, et al.
Publicado: (2017)

Ethanolic Extract of Astragali Radix and Salviae Radix Prohibits Oxidative Brain Injury by Psycho-Emotional Stress in Whisker Removal Rat Model
por: Kim, Hyeong-Geug, et al.
Publicado: (2014)

The Efficacy and Safety of Myelophil, an Ethanol Extract Mixture of Astragali Radix and Salviae Radix, for Chronic Fatigue Syndrome: A Randomized Clinical Trial
por: Joung, Jin-Yong, et al.
Publicado: (2019)

Retracted: Network Pharmacology and Molecular Docking Analysis on Molecular Targets and Mechanisms of “Chuanxiong Rhizoma: Radix Salviae miltiorrhizae” Herb Couples in the Treatment of Preeclampsia
por: and Alternative Medicine, Evidence-Based Complementary
Publicado: (2023)

Efficacy, Chemical Constituents, and Pharmacological Actions of Radix Paeoniae Rubra and Radix Paeoniae Alba
por: Tan, Yu-Qing, et al.
Publicado: (2020)

Radix Salvia miltiorrhiza Ameliorates Burn Injuries by Reducing Inflammation and Promoting Wound Healing
por: Tian, Shuo, et al.
Publicado: (2023)

Immunomodulatory Effects of Hedysarum polybotrys Extract in Mice Macrophages, Splenocytes and Leucopenia
por: Huang, Guan-Cheng, et al.
Publicado: (2013)

Effects of Dark Septate Endophytes on the Performance of Hedysarum scoparium Under Water Deficit Stress
por: Li, Xia, et al.
Publicado: (2019)

Effect of methanol extract of Salviae miltiorrhizae Radix in high-fat diet-induced hyperlipidemic mice
por: Lim, Chiyeon, et al.
Publicado: (2017)

Synergistic study of a Danshen (Salvia Miltiorrhizae Radix et Rhizoma) and Sanqi (Notoginseng Radix et Rhizoma) combination on cell survival in EA.hy926 cells
por: Zhou, Xian, et al.
Publicado: (2019)

Synergistic Effects of Danshen (Salvia Miltiorrhiza Radix et Rhizoma) and Sanqi (Notoginseng Radix et Rhizoma) Combination in Inhibiting Inflammation Mediators in RAW264.7 Cells
por: Zhou, Xian, et al.
Publicado: (2016)

Studies on the active constituents in radix salviae miltiorrhizae and their protective effects on cerebral ischemia reperfusion injury and its mechanism
por: Li, Yan-hui, et al.
Publicado: (2015)

The bioactivity of Hedysarum coronarium extracts on skin enzymes and cells correlates with phenolic content
por: Burlando, Bruno, et al.
Publicado: (2017)

Natural Variation in Physiological Responses of Tunisian Hedysarum carnosum Under Iron Deficiency
por: Ben Abdallah, Heithem, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_blvb4e6q5kghjnjv93hbcf49rc