MLAA-34 knockdown shows enhanced antitumor activity via JAK2/STAT3 signaling pathway in acute monocytic leukemia

MLAA-34 is a novel leukemia-associated gene closely related to the carcinogenesis of acute monocytic leukemia (AML). MLAA-34 over expression has been observed to inhibit apoptosis in vitro. JAK2/STAT3 pathway plays an important role in cell proliferation, differentiation and inhibition of apoptosis...

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Detalles Bibliográficos
Autores principales: Lei, Bo, Qian, Lu, Zhang, Yanping, Chen, Yinxia, Gao, Meili, Shah, Walayat, Cao, Xingmei, Zhang, Pengyu, Zhao, Wanhong, Liu, Jie, Wang, Jianli, Ma, Xiaorong, Yang, Yun, Meng, Xin, Cai, Fengmei, Xu, Yan, Luo, Jing, Wang, Baiyan, Zhang, Yang, He, Aili, Zhang, Wanggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592008/
https://www.ncbi.nlm.nih.gov/pubmed/33123268
http://dx.doi.org/10.7150/jca.46670

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