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Development of an artificial antibody specific for HLA/peptide complex derived from cancer stem-like cell/cancer-initiating cell antigen DNAJB8

BACKGROUND: Peptide-vaccination therapy targeting tumour-associated antigens can elicit immune responses, but cannot be used to eliminate large tumour burden. In this study, we developed a therapeutic single-chain variable-fragment (scFv) antibody that recognises the cancer stem-like cell/cancer-ini...

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Detalles Bibliográficos
Autores principales:	Tadano, Hiroki, Tsukahara, Tomohide, Mizushima, Emi, Akamatsu, Asuka, Watanabe, Kazue, Nojima, Iyori, Kubo, Terufumi, Kanaseki, Takayuki, Hirohashi, Yoshihiko, Sato, Noriyuki, Torigoe, Toshihiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592043/ https://www.ncbi.nlm.nih.gov/pubmed/32753678 http://dx.doi.org/10.1038/s41416-020-1017-1

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