Phosphorylation of Connexin36 near the C-terminus switches binding affinities for PDZ-domain and 14–3–3 proteins in vitro

Connexin36 (Cx36) is the most abundant connexin in central nervous system neurons. It forms gap junction channels that act as electrical synapses. Similar to chemical synapses, Cx36-containing gap junctions undergo activity-dependent plasticity and complex regulation. Cx36 gap junctions represent mu...

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Detalles Bibliográficos
Autores principales: Tetenborg, Stephan, Wang, Helen Y., Nemitz, Lena, Depping, Anne, Espejo, Alexsandra B., Aseervatham, Jaya, Bedford, Mark T., Janssen-Bienhold, Ulrike, O’Brien, John, Dedek, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592057/
https://www.ncbi.nlm.nih.gov/pubmed/33110101
http://dx.doi.org/10.1038/s41598-020-75375-0

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