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Low-dose radiation treatment enhances systemic antitumor immune responses by overcoming the inhibitory stroma
BACKGROUND: Despite some successes with checkpoint inhibitors for treating cancer, most patients remain refractory to treatment, possibly due to the inhibitory nature of the tumor stroma that impedes the function and entry of effector cells. We devised a new technique of combining immunotherapy with...
Autores principales: | Barsoumian, Hampartsoum B, Ramapriyan, Rishab, Younes, Ahmed I, Caetano, Mauricio S, Menon, Hari, Comeaux, Nathan I, Cushman, Taylor R, Schoenhals, Jonathan E, Cadena, Alexandra P, Reilly, Timothy P, Chen, Dawei, Masrorpour, Fatemeh, Li, Ailin, Hong, David S, Diab, Adi, Nguyen, Quynh-Nhu, Glitza, Isabella, Ferrarotto, Renata, Chun, Stephen G, Cortez, Maria Angelica, Welsh, James |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592253/ https://www.ncbi.nlm.nih.gov/pubmed/33106386 http://dx.doi.org/10.1136/jitc-2020-000537 |
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