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Design and synthesis of multi-target directed 1,2,3-triazole-dimethylaminoacryloyl-chromenone derivatives with potential use in Alzheimer's disease

To discover multifunctional agents for the treatment of Alzheimer's disease (AD), a new series of 1,2,3-triazole-chromenone derivatives were designed and synthesized based on the multi target-directed ligands approach. The in vitro biological activities included acetylcholinesterase (AChE) and...

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Detalles Bibliográficos
Autores principales:	Karimi Askarani, Hajar, Iraji, Aida, Rastegari, Arezoo, Abbas Bukhari, Syed Nasir, Firuzi, Omidreza, Akbarzadeh, Tahmineh, Saeedi, Mina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592376/ https://www.ncbi.nlm.nih.gov/pubmed/33134975 http://dx.doi.org/10.1186/s13065-020-00715-0

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