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Impact of extracellular matrix stiffness on genomic heterogeneity in MYCN-amplified neuroblastoma cell line

BACKGROUND: Increased tissue stiffness is a common feature of malignant solid tumors, often associated with metastasis and poor patient outcomes. Vitronectin, as an extracellular matrix anchorage glycoprotein related to a stiff matrix, is present in a particularly increased quantity and specific dis...

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Detalles Bibliográficos
Autores principales: López-Carrasco, Amparo, Martín-Vañó, Susana, Burgos-Panadero, Rebeca, Monferrer, Ezequiel, Berbegall, Ana P., Fernández-Blanco, Beatriz, Navarro, Samuel, Noguera, Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592549/
https://www.ncbi.nlm.nih.gov/pubmed/33109237
http://dx.doi.org/10.1186/s13046-020-01729-1