Exosomes containing miRNAs targeting HER2 synthesis and engineered to adhere to HER2 on tumor cells surface exhibit enhanced antitumor activity

BACKGROUND: Exosomes are small, cellular membrane-derived vesicles with a diameter of 50–150 nm. Exosomes are considered ideal drug delivery systems with a wide range of applications in various diseases, including cancer. However, nonspecific delivery of therapeutic agents by exosomes in vivo remain...

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Detalles Bibliográficos
Autores principales: Wang, Lei, Zhou, Xusha, Zou, Weixuan, Wu, Yinglin, Zhao, Jing, Chen, Xiaoqing, Zhou, Grace Guoying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592554/
https://www.ncbi.nlm.nih.gov/pubmed/33109196
http://dx.doi.org/10.1186/s12951-020-00711-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592554/
https://www.ncbi.nlm.nih.gov/pubmed/33109196
http://dx.doi.org/10.1186/s12951-020-00711-5

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