Cargando…

Mild hypoxia triggers transient blood–brain barrier disruption: a fundamental protective role for microglia

We recently demonstrated that when mice are exposed to chronic mild hypoxia (CMH, 8% O(2)), blood vessels in the spinal cord show transient vascular leak that is associated with clustering and activation of microglia around disrupted vessels. Importantly, microglial depletion profoundly increased hy...

Descripción completa

Detalles Bibliográficos
Autores principales: Halder, Sebok K., Milner, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592567/
https://www.ncbi.nlm.nih.gov/pubmed/33115539
http://dx.doi.org/10.1186/s40478-020-01051-z