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Mild hypoxia triggers transient blood–brain barrier disruption: a fundamental protective role for microglia
We recently demonstrated that when mice are exposed to chronic mild hypoxia (CMH, 8% O(2)), blood vessels in the spinal cord show transient vascular leak that is associated with clustering and activation of microglia around disrupted vessels. Importantly, microglial depletion profoundly increased hy...
Autores principales: | Halder, Sebok K., Milner, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592567/ https://www.ncbi.nlm.nih.gov/pubmed/33115539 http://dx.doi.org/10.1186/s40478-020-01051-z |
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