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Management of Pain in Parkinson’s Disease

Pain is a very frequent symptom with influence on the quality of life in Parkinson’s disease (PD), but is still underdiagnosed and commonly treated only unsystematically. Pain etiology and pain character are often complex and multi-causal, and data regarding treatment recommendations are limited. Pa...

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Detalles Bibliográficos
Autores principales: Buhmann, Carsten, Kassubek, Jan, Jost, Wolfgang H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592654/
https://www.ncbi.nlm.nih.gov/pubmed/32568113
http://dx.doi.org/10.3233/JPD-202069
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author Buhmann, Carsten
Kassubek, Jan
Jost, Wolfgang H.
author_facet Buhmann, Carsten
Kassubek, Jan
Jost, Wolfgang H.
author_sort Buhmann, Carsten
collection PubMed
description Pain is a very frequent symptom with influence on the quality of life in Parkinson’s disease (PD), but is still underdiagnosed and commonly treated only unsystematically. Pain etiology and pain character are often complex and multi-causal, and data regarding treatment recommendations are limited. Pain can be primarily related to PD but frequently it is associated with secondary diseases, such as arthrosis of the spine or joints. However, even basically PD-unrelated pain often is amplified by motor- or non-motor PD symptoms, such as akinesia or depression. Beyond an optimization of anti-parkinsonian treatment, additional pain treatment strategies are usually needed to properly address pain in PD. A careful pain history and diagnostic work-up is essential to rate the underlying pain pathophysiology and to develop a targeted therapeutic concept. This review gives an overview on how pain is treated in PD patients and how patients assess the effectiveness of these therapies; here, the manuscript focuses on pathophysiology-driven suggestions for a multimodal pain management in clinical practice.
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spelling pubmed-75926542020-10-30 Management of Pain in Parkinson’s Disease Buhmann, Carsten Kassubek, Jan Jost, Wolfgang H. J Parkinsons Dis Review Pain is a very frequent symptom with influence on the quality of life in Parkinson’s disease (PD), but is still underdiagnosed and commonly treated only unsystematically. Pain etiology and pain character are often complex and multi-causal, and data regarding treatment recommendations are limited. Pain can be primarily related to PD but frequently it is associated with secondary diseases, such as arthrosis of the spine or joints. However, even basically PD-unrelated pain often is amplified by motor- or non-motor PD symptoms, such as akinesia or depression. Beyond an optimization of anti-parkinsonian treatment, additional pain treatment strategies are usually needed to properly address pain in PD. A careful pain history and diagnostic work-up is essential to rate the underlying pain pathophysiology and to develop a targeted therapeutic concept. This review gives an overview on how pain is treated in PD patients and how patients assess the effectiveness of these therapies; here, the manuscript focuses on pathophysiology-driven suggestions for a multimodal pain management in clinical practice. IOS Press 2020-09-01 /pmc/articles/PMC7592654/ /pubmed/32568113 http://dx.doi.org/10.3233/JPD-202069 Text en © 2020 – IOS Press and the authors. All rights reserved https://creativecommons.org/licenses/by-nc/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial (CC BY-NC 4.0) License (https://creativecommons.org/licenses/by-nc/4.0/) , which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Buhmann, Carsten
Kassubek, Jan
Jost, Wolfgang H.
Management of Pain in Parkinson’s Disease
title Management of Pain in Parkinson’s Disease
title_full Management of Pain in Parkinson’s Disease
title_fullStr Management of Pain in Parkinson’s Disease
title_full_unstemmed Management of Pain in Parkinson’s Disease
title_short Management of Pain in Parkinson’s Disease
title_sort management of pain in parkinson’s disease
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592654/
https://www.ncbi.nlm.nih.gov/pubmed/32568113
http://dx.doi.org/10.3233/JPD-202069
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