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Young Onset Parkinson’s Disease: A Modern and Tailored Approach

In people with young onset Parkinson’s disease (YOPD), onset of symptoms is between 21 and 40 years of age. The distinction between YOPD and late-onset Parkinson’s disease is supported by genetic differences (a genetic etiology is more common in people with YOPD) and clinical differences (e.g., dyst...

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Detalles Bibliográficos
Autores principales: Post, Bart, van den Heuvel, Lieneke, van Prooije, Teije, van Ruissen, Xander, van de Warrenburg, Bart, Nonnekes, Jorik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592661/
https://www.ncbi.nlm.nih.gov/pubmed/32651336
http://dx.doi.org/10.3233/JPD-202135
Descripción
Sumario:In people with young onset Parkinson’s disease (YOPD), onset of symptoms is between 21 and 40 years of age. The distinction between YOPD and late-onset Parkinson’s disease is supported by genetic differences (a genetic etiology is more common in people with YOPD) and clinical differences (e.g., dystonia and levodopa-induced dyskinesias are more common inYOPD). Moreover, people with YOPD tend to have different family and societal engagements compared to those with late-onset PD. These unique features have implications for clinical management, and call for a tailored multidisplinary approach involving shared-decision making.