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Young Onset Parkinson’s Disease: A Modern and Tailored Approach

In people with young onset Parkinson’s disease (YOPD), onset of symptoms is between 21 and 40 years of age. The distinction between YOPD and late-onset Parkinson’s disease is supported by genetic differences (a genetic etiology is more common in people with YOPD) and clinical differences (e.g., dyst...

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Autores principales: Post, Bart, van den Heuvel, Lieneke, van Prooije, Teije, van Ruissen, Xander, van de Warrenburg, Bart, Nonnekes, Jorik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592661/
https://www.ncbi.nlm.nih.gov/pubmed/32651336
http://dx.doi.org/10.3233/JPD-202135
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author Post, Bart
van den Heuvel, Lieneke
van Prooije, Teije
van Ruissen, Xander
van de Warrenburg, Bart
Nonnekes, Jorik
author_facet Post, Bart
van den Heuvel, Lieneke
van Prooije, Teije
van Ruissen, Xander
van de Warrenburg, Bart
Nonnekes, Jorik
author_sort Post, Bart
collection PubMed
description In people with young onset Parkinson’s disease (YOPD), onset of symptoms is between 21 and 40 years of age. The distinction between YOPD and late-onset Parkinson’s disease is supported by genetic differences (a genetic etiology is more common in people with YOPD) and clinical differences (e.g., dystonia and levodopa-induced dyskinesias are more common inYOPD). Moreover, people with YOPD tend to have different family and societal engagements compared to those with late-onset PD. These unique features have implications for clinical management, and call for a tailored multidisplinary approach involving shared-decision making.
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spelling pubmed-75926612020-10-30 Young Onset Parkinson’s Disease: A Modern and Tailored Approach Post, Bart van den Heuvel, Lieneke van Prooije, Teije van Ruissen, Xander van de Warrenburg, Bart Nonnekes, Jorik J Parkinsons Dis Review In people with young onset Parkinson’s disease (YOPD), onset of symptoms is between 21 and 40 years of age. The distinction between YOPD and late-onset Parkinson’s disease is supported by genetic differences (a genetic etiology is more common in people with YOPD) and clinical differences (e.g., dystonia and levodopa-induced dyskinesias are more common inYOPD). Moreover, people with YOPD tend to have different family and societal engagements compared to those with late-onset PD. These unique features have implications for clinical management, and call for a tailored multidisplinary approach involving shared-decision making. IOS Press 2020-09-01 /pmc/articles/PMC7592661/ /pubmed/32651336 http://dx.doi.org/10.3233/JPD-202135 Text en © 2020 – IOS Press and the authors. All rights reserved https://creativecommons.org/licenses/by-nc/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial (CC BY-NC 4.0) License (https://creativecommons.org/licenses/by-nc/4.0/) , which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Post, Bart
van den Heuvel, Lieneke
van Prooije, Teije
van Ruissen, Xander
van de Warrenburg, Bart
Nonnekes, Jorik
Young Onset Parkinson’s Disease: A Modern and Tailored Approach
title Young Onset Parkinson’s Disease: A Modern and Tailored Approach
title_full Young Onset Parkinson’s Disease: A Modern and Tailored Approach
title_fullStr Young Onset Parkinson’s Disease: A Modern and Tailored Approach
title_full_unstemmed Young Onset Parkinson’s Disease: A Modern and Tailored Approach
title_short Young Onset Parkinson’s Disease: A Modern and Tailored Approach
title_sort young onset parkinson’s disease: a modern and tailored approach
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592661/
https://www.ncbi.nlm.nih.gov/pubmed/32651336
http://dx.doi.org/10.3233/JPD-202135
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