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Young Onset Parkinson’s Disease: A Modern and Tailored Approach
In people with young onset Parkinson’s disease (YOPD), onset of symptoms is between 21 and 40 years of age. The distinction between YOPD and late-onset Parkinson’s disease is supported by genetic differences (a genetic etiology is more common in people with YOPD) and clinical differences (e.g., dyst...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592661/ https://www.ncbi.nlm.nih.gov/pubmed/32651336 http://dx.doi.org/10.3233/JPD-202135 |
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author | Post, Bart van den Heuvel, Lieneke van Prooije, Teije van Ruissen, Xander van de Warrenburg, Bart Nonnekes, Jorik |
author_facet | Post, Bart van den Heuvel, Lieneke van Prooije, Teije van Ruissen, Xander van de Warrenburg, Bart Nonnekes, Jorik |
author_sort | Post, Bart |
collection | PubMed |
description | In people with young onset Parkinson’s disease (YOPD), onset of symptoms is between 21 and 40 years of age. The distinction between YOPD and late-onset Parkinson’s disease is supported by genetic differences (a genetic etiology is more common in people with YOPD) and clinical differences (e.g., dystonia and levodopa-induced dyskinesias are more common inYOPD). Moreover, people with YOPD tend to have different family and societal engagements compared to those with late-onset PD. These unique features have implications for clinical management, and call for a tailored multidisplinary approach involving shared-decision making. |
format | Online Article Text |
id | pubmed-7592661 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | IOS Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-75926612020-10-30 Young Onset Parkinson’s Disease: A Modern and Tailored Approach Post, Bart van den Heuvel, Lieneke van Prooije, Teije van Ruissen, Xander van de Warrenburg, Bart Nonnekes, Jorik J Parkinsons Dis Review In people with young onset Parkinson’s disease (YOPD), onset of symptoms is between 21 and 40 years of age. The distinction between YOPD and late-onset Parkinson’s disease is supported by genetic differences (a genetic etiology is more common in people with YOPD) and clinical differences (e.g., dystonia and levodopa-induced dyskinesias are more common inYOPD). Moreover, people with YOPD tend to have different family and societal engagements compared to those with late-onset PD. These unique features have implications for clinical management, and call for a tailored multidisplinary approach involving shared-decision making. IOS Press 2020-09-01 /pmc/articles/PMC7592661/ /pubmed/32651336 http://dx.doi.org/10.3233/JPD-202135 Text en © 2020 – IOS Press and the authors. All rights reserved https://creativecommons.org/licenses/by-nc/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial (CC BY-NC 4.0) License (https://creativecommons.org/licenses/by-nc/4.0/) , which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Post, Bart van den Heuvel, Lieneke van Prooije, Teije van Ruissen, Xander van de Warrenburg, Bart Nonnekes, Jorik Young Onset Parkinson’s Disease: A Modern and Tailored Approach |
title | Young Onset Parkinson’s Disease: A Modern and Tailored Approach |
title_full | Young Onset Parkinson’s Disease: A Modern and Tailored Approach |
title_fullStr | Young Onset Parkinson’s Disease: A Modern and Tailored Approach |
title_full_unstemmed | Young Onset Parkinson’s Disease: A Modern and Tailored Approach |
title_short | Young Onset Parkinson’s Disease: A Modern and Tailored Approach |
title_sort | young onset parkinson’s disease: a modern and tailored approach |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592661/ https://www.ncbi.nlm.nih.gov/pubmed/32651336 http://dx.doi.org/10.3233/JPD-202135 |
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