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The Universal Prescription for Parkinson’s Disease: Exercise

Over the past two decades, aerobic exercise has emerged as a mainstream recommendation to aid in treating Parkinson’s disease (PD). Despite the acknowledgement of the benefits of exercise for people with PD (PwPD), frequently, exercise recommendations lack specificity in terms of frequency, intensit...

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Autores principales: Alberts, Jay L., Rosenfeldt, Anson B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592674/
https://www.ncbi.nlm.nih.gov/pubmed/32925109
http://dx.doi.org/10.3233/JPD-202100
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author Alberts, Jay L.
Rosenfeldt, Anson B.
author_facet Alberts, Jay L.
Rosenfeldt, Anson B.
author_sort Alberts, Jay L.
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description Over the past two decades, aerobic exercise has emerged as a mainstream recommendation to aid in treating Parkinson’s disease (PD). Despite the acknowledgement of the benefits of exercise for people with PD (PwPD), frequently, exercise recommendations lack specificity in terms of frequency, intensity and duration. Additionally, conflating physical activity with exercise has contributed to providing vague exercise recommendations to PwPD. Therefore, the beneficial effects of exercise may not be fully realized in PwPD. Data provided by animal studies and select human trials indicate aerobic exercise may facilitate structural and functional changes in the brain. Recently, several large human clinical trials have been completed and collectively support the use of aerobic exercise, specifically high-intensity aerobic exercise, in improving PD motor symptoms. Data from these and other studies provide the basis to include aerobic exercise as an integral component in treating PD. Based on positive clinical findings and trials, it is advised that PwPD perform aerobic exercise in the following dose: 3x/week, 30–40-minute main exercise set, 60–80% of heart rate reserve or 70–85% of heart rate max. In lieu of heart rate, individuals can achieve an intensity of 14–17 on a 20-point RPE scale. Ongoing clinical trials, SPARX3 and CYCLE-II, have potential to further develop patient-specific exercise recommendations through prognostic modeling.
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spelling pubmed-75926742020-10-30 The Universal Prescription for Parkinson’s Disease: Exercise Alberts, Jay L. Rosenfeldt, Anson B. J Parkinsons Dis Review Over the past two decades, aerobic exercise has emerged as a mainstream recommendation to aid in treating Parkinson’s disease (PD). Despite the acknowledgement of the benefits of exercise for people with PD (PwPD), frequently, exercise recommendations lack specificity in terms of frequency, intensity and duration. Additionally, conflating physical activity with exercise has contributed to providing vague exercise recommendations to PwPD. Therefore, the beneficial effects of exercise may not be fully realized in PwPD. Data provided by animal studies and select human trials indicate aerobic exercise may facilitate structural and functional changes in the brain. Recently, several large human clinical trials have been completed and collectively support the use of aerobic exercise, specifically high-intensity aerobic exercise, in improving PD motor symptoms. Data from these and other studies provide the basis to include aerobic exercise as an integral component in treating PD. Based on positive clinical findings and trials, it is advised that PwPD perform aerobic exercise in the following dose: 3x/week, 30–40-minute main exercise set, 60–80% of heart rate reserve or 70–85% of heart rate max. In lieu of heart rate, individuals can achieve an intensity of 14–17 on a 20-point RPE scale. Ongoing clinical trials, SPARX3 and CYCLE-II, have potential to further develop patient-specific exercise recommendations through prognostic modeling. IOS Press 2020-09-01 /pmc/articles/PMC7592674/ /pubmed/32925109 http://dx.doi.org/10.3233/JPD-202100 Text en © 2020 – IOS Press and the authors. All rights reserved https://creativecommons.org/licenses/by-nc/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial (CC BY-NC 4.0) License (https://creativecommons.org/licenses/by-nc/4.0/) , which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Alberts, Jay L.
Rosenfeldt, Anson B.
The Universal Prescription for Parkinson’s Disease: Exercise
title The Universal Prescription for Parkinson’s Disease: Exercise
title_full The Universal Prescription for Parkinson’s Disease: Exercise
title_fullStr The Universal Prescription for Parkinson’s Disease: Exercise
title_full_unstemmed The Universal Prescription for Parkinson’s Disease: Exercise
title_short The Universal Prescription for Parkinson’s Disease: Exercise
title_sort universal prescription for parkinson’s disease: exercise
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592674/
https://www.ncbi.nlm.nih.gov/pubmed/32925109
http://dx.doi.org/10.3233/JPD-202100
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