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Spontaneous restoration of functional β‐cell mass in obese SM/J mice

Maintenance of functional β‐cell mass is critical to preventing diabetes, but the physiological mechanisms that cause β‐cell populations to thrive or fail in the context of obesity are unknown. High fat‐fed SM/J mice spontaneously transition from hyperglycemic‐obese to normoglycemic‐obese with age,...

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Detalles Bibliográficos
Autores principales: Miranda, Mario A., Carson, Caryn, St. Pierre, Celine L., Macias‐Velasco, Juan F., Hughes, Jing W., Kunzmann, Marcus, Schmidt, Heather, Wayhart, Jessica P., Lawson, Heather A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592878/
https://www.ncbi.nlm.nih.gov/pubmed/33113267
http://dx.doi.org/10.14814/phy2.14573