The HIV-1 latent reservoir is largely sensitive to circulating T cells

HIV-1-specific CD8+ T cells are an important component of HIV-1 curative strategies. Viral variants in the HIV-1 reservoir may limit the capacity of T cells to detect and clear virus-infected cells. We investigated the patterns of T cell escape variants in the replication-competent reservoir of 25 p...

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Detalles Bibliográficos
Autores principales: Warren, Joanna A, Zhou, Shuntai, Xu, Yinyan, Moeser, Matthew J, MacMillan, Daniel R, Council, Olivia, Kirchherr, Jennifer, Sung, Julia M, Roan, Nadia R, Adimora, Adaora A, Joseph, Sarah, Kuruc, JoAnn D, Gay, Cynthia L, Margolis, David M, Archin, Nancie, Brumme, Zabrina L, Swanstrom, Ronald, Goonetilleke, Nilu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593086/
https://www.ncbi.nlm.nih.gov/pubmed/33021198
http://dx.doi.org/10.7554/eLife.57246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593086/
https://www.ncbi.nlm.nih.gov/pubmed/33021198
http://dx.doi.org/10.7554/eLife.57246

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