CyberKnife Radiotherapy for Skull Base Petroclival Metastases Including Dorello’s Canal: Report of 10 Cases

Skull base petroclival metastases cause diplopia due to abducens nerve palsy. Diplopia is visually disabling, and skull base metastasis is extremely difficult to treat even with microscopic surgery. However, stereotactic radiotherapy with CyberKnife (Accuray Incorporated, Sunnyvale, California) has...

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Detalles Bibliográficos
Autores principales: Miyazaki, Shinichiro, Harada, Yuko, Sasaki, Yusuke, Fukushima, Takanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Radiation Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593206/
https://www.ncbi.nlm.nih.gov/pubmed/33133857
http://dx.doi.org/10.7759/cureus.10692
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author Miyazaki, Shinichiro
Harada, Yuko
Sasaki, Yusuke
Fukushima, Takanori
author_facet Miyazaki, Shinichiro
Harada, Yuko
Sasaki, Yusuke
Fukushima, Takanori
author_sort Miyazaki, Shinichiro
collection PubMed
description Skull base petroclival metastases cause diplopia due to abducens nerve palsy. Diplopia is visually disabling, and skull base metastasis is extremely difficult to treat even with microscopic surgery. However, stereotactic radiotherapy with CyberKnife (Accuray Incorporated, Sunnyvale, California) has been very successful in 10 cases. As the abducens nerve runs through Dorello’s canal in the skull base, the radiation dose and fraction were adjusted to avoid damage to the nerve. Since these metastases are not located inside the brain but in the skull base, contrast magnetic resonance imaging (MRI) combined with fluorodeoxyglucose-positron emission tomography (FDG-PET) was essential to detect the cancers.
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spelling pubmed-75932062020-10-30 CyberKnife Radiotherapy for Skull Base Petroclival Metastases Including Dorello’s Canal: Report of 10 Cases Miyazaki, Shinichiro Harada, Yuko Sasaki, Yusuke Fukushima, Takanori Cureus Radiation Oncology Skull base petroclival metastases cause diplopia due to abducens nerve palsy. Diplopia is visually disabling, and skull base metastasis is extremely difficult to treat even with microscopic surgery. However, stereotactic radiotherapy with CyberKnife (Accuray Incorporated, Sunnyvale, California) has been very successful in 10 cases. As the abducens nerve runs through Dorello’s canal in the skull base, the radiation dose and fraction were adjusted to avoid damage to the nerve. Since these metastases are not located inside the brain but in the skull base, contrast magnetic resonance imaging (MRI) combined with fluorodeoxyglucose-positron emission tomography (FDG-PET) was essential to detect the cancers. Cureus 2020-09-28 /pmc/articles/PMC7593206/ /pubmed/33133857 http://dx.doi.org/10.7759/cureus.10692 Text en Copyright © 2020, Miyazaki et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Radiation Oncology
Miyazaki, Shinichiro
Harada, Yuko
Sasaki, Yusuke
Fukushima, Takanori
CyberKnife Radiotherapy for Skull Base Petroclival Metastases Including Dorello’s Canal: Report of 10 Cases
title CyberKnife Radiotherapy for Skull Base Petroclival Metastases Including Dorello’s Canal: Report of 10 Cases
title_full CyberKnife Radiotherapy for Skull Base Petroclival Metastases Including Dorello’s Canal: Report of 10 Cases
title_fullStr CyberKnife Radiotherapy for Skull Base Petroclival Metastases Including Dorello’s Canal: Report of 10 Cases
title_full_unstemmed CyberKnife Radiotherapy for Skull Base Petroclival Metastases Including Dorello’s Canal: Report of 10 Cases
title_short CyberKnife Radiotherapy for Skull Base Petroclival Metastases Including Dorello’s Canal: Report of 10 Cases
title_sort cyberknife radiotherapy for skull base petroclival metastases including dorello’s canal: report of 10 cases
topic Radiation Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593206/
https://www.ncbi.nlm.nih.gov/pubmed/33133857
http://dx.doi.org/10.7759/cureus.10692
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