Zoledronic Acid in a Mouse Model of Human Fibrous Dysplasia: Ineffectiveness on Tissue Pathology, Formation of “Giant Osteoclasts” and Pathogenetic Implications

We compared the effects of a nitrogen-containing bisphosphonate (N-BP), zoledronic acid (ZA), and an anti-mouse RANKL antibody (anti-mRANKL Ab) on the bone tissue pathology of a transgenic mouse model of human fibrous dysplasia (FD). For comparison, we also reviewed the histological samples of a chi...

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Detalles Bibliográficos
Autores principales: Corsi, Alessandro, Palmisano, Biagio, Spica, Emanuela, Di Filippo, Annamaria, Coletta, Ilenia, Dello Spedale Venti, Michele, Labella, Rossella, Fabretti, Francesca, Donsante, Samantha, Remoli, Cristina, Serafini, Marta, Riminucci, Mara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593313/
https://www.ncbi.nlm.nih.gov/pubmed/32875378
http://dx.doi.org/10.1007/s00223-020-00752-w

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