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p38 and Casein Kinase 2 Mediate Ribonuclease 1 Repression in Inflamed Human Endothelial Cells via Promoter Remodeling Through Nucleosome Remodeling and Deacetylase Complex

Vascular pathologies, such as thrombosis or atherosclerosis, are leading causes of death worldwide and are strongly associated with the dysfunction of vascular endothelial cells. In this context, the extracellular endonuclease Ribonuclease 1 (RNase1) acts as an essential protective factor in regulat...

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Detalles Bibliográficos
Autores principales: Bedenbender, Katrin, Beinborn, Isabell, Vollmeister, Evelyn, Schmeck, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593526/
https://www.ncbi.nlm.nih.gov/pubmed/33178683
http://dx.doi.org/10.3389/fcell.2020.563604