Cargando…
An Expanded Genetic Code Enables Trimethylamine Metabolism in Human Gut Bacteria
Cardiovascular disease (CVD) has been linked to animal-based diets, which are a major source of trimethylamine (TMA), a precursor of the proatherogenic compound trimethylamine-N-oxide (TMAO). Human gut bacteria in the genus Bilophila have genomic signatures for genetic code expansion that could enab...
Autores principales: | Kivenson, Veronika, Giovannoni, Stephen J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593587/ https://www.ncbi.nlm.nih.gov/pubmed/33109749 http://dx.doi.org/10.1128/mSystems.00413-20 |
Ejemplares similares
-
Uncovering the trimethylamine-producing bacteria of the human gut microbiota
por: Rath, Silke, et al.
Publicado: (2017) -
An Ecological Basis for Dual Genetic Code Expansion in Marine Deltaproteobacteria
por: Kivenson, Veronika, et al.
Publicado: (2021) -
Elucidation of an anaerobic pathway for metabolism of l-carnitine–derived γ-butyrobetaine to trimethylamine in human gut bacteria
por: Rajakovich, Lauren J., et al.
Publicado: (2021) -
Metabolic retroconversion of trimethylamine N-oxide and the gut microbiota
por: Hoyles, Lesley, et al.
Publicado: (2018) -
Expanded Genetic Codes in Next Generation Sequencing Enable Decontamination and Mitochondrial Enrichment
por: McKernan, Kevin J., et al.
Publicado: (2014)