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Diffuse alveolar hemorrhage, a rare presentation of polymyositis
BACKGROUND: Diffuse alveolar hemorrhage is a medical emergency caused by persistent and recurrent pulmonary hemorrhage [1]. It is an uncommon presentation of polymyositis. Symptoms of polymyositis include fatigue, muscle pains, proximal muscle weakness, and joint pains [2]. CASE PRESENTATION: A 44-y...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593619/ https://www.ncbi.nlm.nih.gov/pubmed/33145158 http://dx.doi.org/10.1016/j.rmcr.2020.101261 |
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author | Samuel, Sharoon Brown, Brent Mason, Nita Abdo, Tony |
author_facet | Samuel, Sharoon Brown, Brent Mason, Nita Abdo, Tony |
author_sort | Samuel, Sharoon |
collection | PubMed |
description | BACKGROUND: Diffuse alveolar hemorrhage is a medical emergency caused by persistent and recurrent pulmonary hemorrhage [1]. It is an uncommon presentation of polymyositis. Symptoms of polymyositis include fatigue, muscle pains, proximal muscle weakness, and joint pains [2]. CASE PRESENTATION: A 44-year-old male presented with new onset shortness of breath and productive cough with white sputum and occasional hemoptysis. The patient was diagnosed with diffuse alveolar hemorrhage (DAH) via bronchoscopy and discharged initially on prednisone. The patient's laboratory work indicated positive titers of ANA & anti-Jo-1 antibody with low complement levels. These results pointed towards the diagnosis of polymyositis [3]. DAH can also be caused by systemic lupus erythematosus, Goodpasture's syndrome, Sjogren syndrome, anticoagulant therapy, and antiphospholipid antibody syndrome [4]. However, the possibility of these potential causes was excluded. CONCLUSION: This case of diffuse alveolar hemorrhage was most likely due to polymyositis. |
format | Online Article Text |
id | pubmed-7593619 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-75936192020-11-02 Diffuse alveolar hemorrhage, a rare presentation of polymyositis Samuel, Sharoon Brown, Brent Mason, Nita Abdo, Tony Respir Med Case Rep Case Report BACKGROUND: Diffuse alveolar hemorrhage is a medical emergency caused by persistent and recurrent pulmonary hemorrhage [1]. It is an uncommon presentation of polymyositis. Symptoms of polymyositis include fatigue, muscle pains, proximal muscle weakness, and joint pains [2]. CASE PRESENTATION: A 44-year-old male presented with new onset shortness of breath and productive cough with white sputum and occasional hemoptysis. The patient was diagnosed with diffuse alveolar hemorrhage (DAH) via bronchoscopy and discharged initially on prednisone. The patient's laboratory work indicated positive titers of ANA & anti-Jo-1 antibody with low complement levels. These results pointed towards the diagnosis of polymyositis [3]. DAH can also be caused by systemic lupus erythematosus, Goodpasture's syndrome, Sjogren syndrome, anticoagulant therapy, and antiphospholipid antibody syndrome [4]. However, the possibility of these potential causes was excluded. CONCLUSION: This case of diffuse alveolar hemorrhage was most likely due to polymyositis. Elsevier 2020-10-17 /pmc/articles/PMC7593619/ /pubmed/33145158 http://dx.doi.org/10.1016/j.rmcr.2020.101261 Text en © 2020 Published by Elsevier Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Samuel, Sharoon Brown, Brent Mason, Nita Abdo, Tony Diffuse alveolar hemorrhage, a rare presentation of polymyositis |
title | Diffuse alveolar hemorrhage, a rare presentation of polymyositis |
title_full | Diffuse alveolar hemorrhage, a rare presentation of polymyositis |
title_fullStr | Diffuse alveolar hemorrhage, a rare presentation of polymyositis |
title_full_unstemmed | Diffuse alveolar hemorrhage, a rare presentation of polymyositis |
title_short | Diffuse alveolar hemorrhage, a rare presentation of polymyositis |
title_sort | diffuse alveolar hemorrhage, a rare presentation of polymyositis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593619/ https://www.ncbi.nlm.nih.gov/pubmed/33145158 http://dx.doi.org/10.1016/j.rmcr.2020.101261 |
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