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Diffuse alveolar hemorrhage, a rare presentation of polymyositis

BACKGROUND: Diffuse alveolar hemorrhage is a medical emergency caused by persistent and recurrent pulmonary hemorrhage [1]. It is an uncommon presentation of polymyositis. Symptoms of polymyositis include fatigue, muscle pains, proximal muscle weakness, and joint pains [2]. CASE PRESENTATION: A 44-y...

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Detalles Bibliográficos
Autores principales: Samuel, Sharoon, Brown, Brent, Mason, Nita, Abdo, Tony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593619/
https://www.ncbi.nlm.nih.gov/pubmed/33145158
http://dx.doi.org/10.1016/j.rmcr.2020.101261
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author Samuel, Sharoon
Brown, Brent
Mason, Nita
Abdo, Tony
author_facet Samuel, Sharoon
Brown, Brent
Mason, Nita
Abdo, Tony
author_sort Samuel, Sharoon
collection PubMed
description BACKGROUND: Diffuse alveolar hemorrhage is a medical emergency caused by persistent and recurrent pulmonary hemorrhage [1]. It is an uncommon presentation of polymyositis. Symptoms of polymyositis include fatigue, muscle pains, proximal muscle weakness, and joint pains [2]. CASE PRESENTATION: A 44-year-old male presented with new onset shortness of breath and productive cough with white sputum and occasional hemoptysis. The patient was diagnosed with diffuse alveolar hemorrhage (DAH) via bronchoscopy and discharged initially on prednisone. The patient's laboratory work indicated positive titers of ANA & anti-Jo-1 antibody with low complement levels. These results pointed towards the diagnosis of polymyositis [3]. DAH can also be caused by systemic lupus erythematosus, Goodpasture's syndrome, Sjogren syndrome, anticoagulant therapy, and antiphospholipid antibody syndrome [4]. However, the possibility of these potential causes was excluded. CONCLUSION: This case of diffuse alveolar hemorrhage was most likely due to polymyositis.
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spelling pubmed-75936192020-11-02 Diffuse alveolar hemorrhage, a rare presentation of polymyositis Samuel, Sharoon Brown, Brent Mason, Nita Abdo, Tony Respir Med Case Rep Case Report BACKGROUND: Diffuse alveolar hemorrhage is a medical emergency caused by persistent and recurrent pulmonary hemorrhage [1]. It is an uncommon presentation of polymyositis. Symptoms of polymyositis include fatigue, muscle pains, proximal muscle weakness, and joint pains [2]. CASE PRESENTATION: A 44-year-old male presented with new onset shortness of breath and productive cough with white sputum and occasional hemoptysis. The patient was diagnosed with diffuse alveolar hemorrhage (DAH) via bronchoscopy and discharged initially on prednisone. The patient's laboratory work indicated positive titers of ANA & anti-Jo-1 antibody with low complement levels. These results pointed towards the diagnosis of polymyositis [3]. DAH can also be caused by systemic lupus erythematosus, Goodpasture's syndrome, Sjogren syndrome, anticoagulant therapy, and antiphospholipid antibody syndrome [4]. However, the possibility of these potential causes was excluded. CONCLUSION: This case of diffuse alveolar hemorrhage was most likely due to polymyositis. Elsevier 2020-10-17 /pmc/articles/PMC7593619/ /pubmed/33145158 http://dx.doi.org/10.1016/j.rmcr.2020.101261 Text en © 2020 Published by Elsevier Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Samuel, Sharoon
Brown, Brent
Mason, Nita
Abdo, Tony
Diffuse alveolar hemorrhage, a rare presentation of polymyositis
title Diffuse alveolar hemorrhage, a rare presentation of polymyositis
title_full Diffuse alveolar hemorrhage, a rare presentation of polymyositis
title_fullStr Diffuse alveolar hemorrhage, a rare presentation of polymyositis
title_full_unstemmed Diffuse alveolar hemorrhage, a rare presentation of polymyositis
title_short Diffuse alveolar hemorrhage, a rare presentation of polymyositis
title_sort diffuse alveolar hemorrhage, a rare presentation of polymyositis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593619/
https://www.ncbi.nlm.nih.gov/pubmed/33145158
http://dx.doi.org/10.1016/j.rmcr.2020.101261
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