Non-Canonical WNT5A Signaling Through RYK Contributes to Aggressive Phenotype of the Rheumatoid Fibroblast-Like Synoviocytes

We hypothesized that WNT5A could contribute to the enhanced migration and invasiveness of rheumatoid arthritis fibroblast-like synoviocytes (RA FLS), which is one of the incompletely understood aspects of the RA FLS aggressive phenotype. This hypothesis is based on the previous evidence of a WNT5A r...

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Detalles Bibliográficos
Autores principales: Rodriguez-Trillo, Angela, Mosquera, Nerea, Pena, Carmen, Rivas-Tobío, Fatima, Mera-Varela, Antonio, Gonzalez, Antonio, Conde, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593687/
https://www.ncbi.nlm.nih.gov/pubmed/33178184
http://dx.doi.org/10.3389/fimmu.2020.555245

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