Cargando…

A Network Pharmacology-Based Identification Study on the Mechanism of Xiao-Xu-Ming Decoction for Cerebral Ischemic Stroke

OBJECTIVE: We used the network pharmacological analysis method to explore the mechanism of multicomponent, multitarget, and multiway actions of Xiao-Xu-Ming decoction (XXMD) for cerebral ischemic stroke (CIS), which provided a basis on the research of innovative drugs. METHOD: We used the Traditiona...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, De-Hui, Su, Yi-Fan, Sun, Chun-Xia, Fan, Huan-Fang, Gao, Wei-Juan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593742/ https://www.ncbi.nlm.nih.gov/pubmed/33133212 http://dx.doi.org/10.1155/2020/2507074

Ejemplares similares

Network Pharmacology-Based Analysis of Xiao-Xu-Ming Decoction on the Treatment of Alzheimer’s Disease
por: Shen, Yanjia, et al.
Publicado: (2020)

Perturbed Lipidomic Profiles in Rats With Chronic Cerebral Ischemia Are Regulated by Xiao-Xu-Ming Decoction
por: Jia, Zhixin, et al.
Publicado: (2019)

Xiao-Xu-Ming Decoction Reduced Mitophagy Activation and Improved Mitochondrial Function in Cerebral Ischemia and Reperfusion Injury
por: Lan, Rui, et al.
Publicado: (2018)

Xiao-Xu-Ming decoction extract regulates differentially expressed proteins in the hippocampus after chronic cerebral hypoperfusion
por: Wang, Yue-Hua, et al.
Publicado: (2019)

Detecting Key Functional Components Group and Speculating the Potential Mechanism of Xiao-Xu-Ming Decoction in Treating Stroke
por: Chen, Yu-peng, et al.
Publicado: (2022)

Corrigendum: Detecting key functional components group and speculating the potential mechanism of Xiao-Xu-Ming decoction in treating stroke
por: Chen, Yu-peng, et al.
Publicado: (2023)

Xiao-Xu-Ming Decoction Protects against Blood-Brain Barrier Disruption and Neurological Injury Induced by Cerebral Ischemia and Reperfusion in Rats
por: Lan, Rui, et al.
Publicado: (2013)

Erratum to “Xiao-Xu-Ming Decoction Protects against Blood-Brain Barrier Disruption and Neurological Injury Induced by Cerebral Ischemia and Reperfusion in Rats”
por: Lan, Rui, et al.
Publicado: (2013)

PI3K/Akt Pathway Contributes to Neurovascular Unit Protection of Xiao-Xu-Ming Decoction against Focal Cerebral Ischemia and Reperfusion Injury in Rats
por: Lan, Rui, et al.
Publicado: (2013)

Protective Effect of Xiao-Xu-Ming Decoction-Mediated Inhibition of ROS/NLRP3 Axis on Lipopolysaccharide-Induced Acute Lung Injury In Vitro and In Vivo
por: Xiang, Yijin, et al.
Publicado: (2021)

Network pharmacology and experimental evidence reveal the protective mechanism of Yi-Qi Cong-Ming decoction on age-related hearing loss
por: Yang, Yi-Fang, et al.
Publicado: (2022)

A Systems Pharmacology Approach for Identifying the Multiple Mechanisms of Action of the Wei Pi Xiao Decoction for the Treatment of Gastric Precancerous Lesions
por: Yang, Liangjun, et al.
Publicado: (2019)

Improvement of inflammatory response and gastrointestinal function in perioperative of cholelithiasis by Modified Xiao-Cheng-Qi decoction
por: Sun, Bao-Fang, et al.
Publicado: (2023)

Mechanism of Anti-Inflammatory and Antibacterial Effects of QingXiaoWuWei Decoction Based on Network Pharmacology, Molecular Docking and In Vitro Experiments
por: Zhang, Qian, et al.
Publicado: (2021)

Mechanical Study of Jian-Gan-Xiao-Zhi Decoction on Nonalcoholic Fatty Liver Disease Based on Integrated Network Pharmacology and Untargeted Metabolomics
por: Cao, Yong-Jun, et al.
Publicado: (2022)

Mechanism of Huoxue Tongluo Decoction in treatment of erectile dysfunction caused by ischemic stroke based on network pharmacology
por: Wang, Ji-sheng, et al.
Publicado: (2021)

Mechanisms of Antiulcer Effect of an Active Ingredient Group of Modified Xiao Chaihu Decoction
por: Liu, Wei, et al.
Publicado: (2018)

Network pharmacology-based prediction of the active compounds and mechanism of Buyang Huanwu Decoction for ischemic stroke
por: Wang, Kai, et al.
Publicado: (2021)

Mechanism of Sanhua Decoction in the Treatment of Ischemic Stroke Based on Network Pharmacology Methods and Experimental Verification
por: YingHuang,, et al.
Publicado: (2022)

Chemical characterization and metabolic profiling of Xiao-Er-An-Shen Decoction by UPLC-QTOF/MS
por: Yang, Ruipei, et al.
Publicado: (2023)

Dr. Tian Xu
por: Ni, Thomas, et al.
Publicado: (2007)

Network Pharmacology and Molecular Docking Analysis on Molecular Targets and Mechanisms of Buyang Huanwu Decoction in the Treatment of Ischemic Stroke
por: Gao, Qiang, et al.
Publicado: (2021)

Network pharmacology evaluation of the active ingredients and potential targets of XiaoLuoWan for application to uterine fibroids
por: Yu, Yonghui, et al.
Publicado: (2020)

Identification of the active compounds and significant pathways of yinchenhao decoction based on network pharmacology
por: Huang, Jihan, et al.
Publicado: (2017)

Effect of oral Xiao-xian decoction combined with acupoint application therapy on pediatric adenoid hypertrophy: A randomized trial
por: Zhao, Xue, et al.
Publicado: (2023)

Gu-Ben-Fang-Xiao Decoction Ameliorated Murine Asthma in Remission Stage by Modulating Microbiota-Acetate-Tregs Axis
por: Dong, Yingmei, et al.
Publicado: (2020)

A conversation with Yuk Ming Dennis Lo
por: Neill, Ushma S.
Publicado: (2022)

Proteomic Analysis Provides Insights Into the Therapeutic Effect of GU-BEN-FANG-XIAO Decoction on a Persistent Asthmatic Mouse Model
por: Liu, Li-wei, et al.
Publicado: (2019)

First person – De-Li Xu
Publicado: (2018)

Network pharmacology approach and experimental verification of Dan-Shen Decoction in the treatment of ischemic heart disease
por: Gong, Difei, et al.
Publicado: (2022)

Network Pharmacology Analysis and Experimental Verification Strategies Reveal the Action Mechanism of Danshen Decoction in Treating Ischemic Cardiomyopathy
por: Liu, Mengnan, et al.
Publicado: (2022)

Quantitative proteomic analysis of Bi Zhong Xiao decoction against collagen-induced arthritis rats in the early and late stages
por: He, Cailin, et al.
Publicado: (2022)

Transcriptome and Gut Microbiota Profiling Analysis of ANIT-Induced Cholestasis and the Effects of Da-Huang-Xiao-Shi Decoction Intervention
por: Wang, Wang, et al.
Publicado: (2022)

Antithrombotic effects of Huanglian Jiedu decoction in a rat model of ischaemia-reperfusion-induced cerebral stroke
por: Liu, Huan, et al.
Publicado: (2021)

Understanding the polypharmacological anticancer effects of Xiao Chai Hu Tang via a computational pharmacological model
por: ZHENG, CHUN-SONG, et al.
Publicado: (2014)

Network Pharmacology and Experimental Validation to Reveal the Pharmacological Mechanisms of Chongcaoyishen Decoction Against Chronic Kidney Disease
por: Fan, Zhenliang, et al.
Publicado: (2022)

Effect of Hua Yu Xiao Zheng decoction on the expression levels of vascular endothelial growth factor and angiopoietin-2 in rats with endometriosis
por: Chen, Zhen-Zhen, et al.
Publicado: (2017)

Wu-Tou Decoction in Rheumatoid Arthritis: Integrating Network Pharmacology and In Vivo Pharmacological Evaluation
por: Guo, Qingqing, et al.
Publicado: (2017)

Network pharmacology and molecular docking study on the mechanism of colorectal cancer treatment using Xiao-Chai-Hu-Tang
por: Jin, Jingyun, et al.
Publicado: (2021)

Integrating Metabolomics and Network Pharmacology to Explore the Mechanism of Xiao-Yao-San in the Treatment of Inflammatory Response in CUMS Mice
por: Zhang, Yi, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_env022t0vi0am52n6ga37rjueu