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Localized Interleukin-12 for Cancer Immunotherapy
Interleukin-12 (IL-12) is a potent, pro-inflammatory type 1 cytokine that has long been studied as a potential immunotherapy for cancer. Unfortunately, IL-12's remarkable antitumor efficacy in preclinical models has yet to be replicated in humans. Early clinical trials in the mid-1990's sh...
Autores principales: | Nguyen, Khue G., Vrabel, Maura R., Mantooth, Siena M., Hopkins, Jared J., Wagner, Ethan S., Gabaldon, Taylor A., Zaharoff, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593768/ https://www.ncbi.nlm.nih.gov/pubmed/33178203 http://dx.doi.org/10.3389/fimmu.2020.575597 |
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