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In vivo Analysis of CRISPR/Cas9 Induced Atlastin Pathological Mutations in Drosophila
The endoplasmic reticulum (ER) is a highly dynamic network whose shape is thought to be actively regulated by membrane resident proteins. Mutation of several such morphology regulators cause the neurological disorder Hereditary Sp astic Paraplegia (HSP), suggesting a critical role of ER shape mainte...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593789/ https://www.ncbi.nlm.nih.gov/pubmed/33177972 http://dx.doi.org/10.3389/fnins.2020.547746 |