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Ancient but Not Forgotten: New Insights Into MPEG1, a Macrophage Perforin-Like Immune Effector

Macrophage-expressed gene 1 [MPEG1/Perforin-2 (PRF2)] is an ancient metazoan protein belonging to the Membrane Attack Complex/Perforin (MACPF) branch of the MACPF/Cholesterol Dependent Cytolysin (CDC) superfamily of pore-forming proteins (PFPs). MACPF/CDC proteins are a large and extremely diverse s...

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Detalles Bibliográficos
Autores principales:	Bayly-Jones, Charles, Pang, Siew Siew, Spicer, Bradley A., Whisstock, James C., Dunstone, Michelle A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593815/ https://www.ncbi.nlm.nih.gov/pubmed/33178209 http://dx.doi.org/10.3389/fimmu.2020.581906

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