Pharmacological Chaperones Attenuate the Development of Opioid Tolerance

Opioids are potent analgesics widely used to control acute and chronic pain, but long-term use induces tolerance that reduces their effectiveness. Opioids such as morphine bind to mu opioid receptors (MORs), and several downstream signaling pathways are capable of inducing tolerance. We previously r...

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Detalles Bibliográficos
Autores principales: Okuyama, Youta, Jin, Hisayo, Kokubun, Hiroshi, Aoe, Tomohiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593907/
https://www.ncbi.nlm.nih.gov/pubmed/33066035
http://dx.doi.org/10.3390/ijms21207536

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593907/
https://www.ncbi.nlm.nih.gov/pubmed/33066035
http://dx.doi.org/10.3390/ijms21207536

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